首都医科大学学报 ›› 2008, Vol. 29 ›› Issue (4): 436-439.

• 专题报道 • 上一篇    下一篇

糖原合成酶激酶3与双相情感障碍

李晓虹, 刘敏, 罗小年, 王刚   

  1. 首都医科大学附属北京安定医院
  • 收稿日期:2008-06-08 修回日期:1900-01-01 出版日期:2008-08-24 发布日期:2008-08-24
  • 通讯作者: 王刚

Glycogen Synthase Kinase 3 and Bipolar Mood Disorder

Li Xiaohong, Liu Min, Luo Xiaonian, Wang Gang   

  1. Beijing Anding Hospital, Capital Medical University
  • Received:2008-06-08 Revised:1900-01-01 Online:2008-08-24 Published:2008-08-24

摘要: 介绍糖原合成酶激酶3(GSK3)的特性、致凋亡作用以及GSK3与双相障碍治疗药物和动物模型研究,探讨其在双相障碍发生发展和药物治疗中的地位和作用.

关键词: 糖原合成酶激酶3, 双相情感障碍, 转录因子, 锂盐

Abstract: To understand the role of glycogen synthase kinase 3(GSK3) in drug treatment and development of bipolar affective disorder,we introdued the biological features and promotion in apoptosis of GSK3 first.Then,we also reviewed some works of GSK3 in therapeutic drugs and animal models with bipolar affective disorder.

Key words: glycogen synthase 3, bipolar affective disorder, transcription factor, lithium salt

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