首都医科大学学报 ›› 2009, Vol. 30 ›› Issue (5): 710-713.doi: 10.3969/j.issn.1006-7795.2009.05.029

• 综述 • 上一篇    下一篇

HIV/AIDS患者免疫重建炎性综合征研究进展

吴巍, 黄世敬, 王阶   

  1. 中国中医科学院广安门医院免疫重建项目办公室
  • 收稿日期:2009-05-05 修回日期:1900-01-01 出版日期:2009-10-21 发布日期:2009-10-21
  • 通讯作者: 黄世敬

Progresses in Studies on Immune Reconstitution Inflammatory Syndrome in HIV/AIDS Patients

WU Wei, HUANG Shi-jing, WANG Jie   

  1. Immune Reconstritution Program Office, Guang'anmen Hospital,China Academy of Chinese Medical Sciences
  • Received:2009-05-05 Revised:1900-01-01 Online:2009-10-21 Published:2009-10-21

摘要: 免疫重建炎性综合征发生于艾滋病患者应用高效抗反转录病毒疗法后的免疫重建过程中,本文分别对其概念、发病机制、诊断、临床表现和治疗等方面进行了综述。综合文献资料认为在病人的诊治上最重要的一点是提高对免疫重建炎性综合征的诊断和鉴别,以免延误病情。免疫重建的特征之一是恢复了针对机会性感染致病原的免疫反应,因此除非有可能威胁患者生命或导致高致残率外,都应继续应用高效抗反转录病毒疗法。

关键词: HIV/AIDS, 高效抗反转录病毒疗法, 免疫重建炎性综合征

Abstract: Immune reconstitution inflammatory syndrome (IRIS) occurred in the process of immune reconstitution disease after highly active antiretroviral therapy. In this paper, the concept, diagnostic criteria, clinical manifestations and treatment of IRIS were reviewed. It is important to improve diagnosis and differentiation of the IRIS and reduce delays. One of the characteristics of immune reconstitution is restoration of immune response to opportunistic infections . Therefore, unless there is a threat to patient's life or a risk that may lead to a very high rate of disability, the highly active antiretroviral therapy should be continued.

Key words: HIV/AIDS, highly active antiretroviral therapy, immune reconstitution inflammatory syndrome

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