关键词: 糖尿病, 血糖波动, 自我监测

Abstract: Objective The values of the mean blood glucose(MBG) and the mean amplitude of glycemic excursions(MAGE) obtained by continuous glucose monitoring system(CGMS) were compared with those obtained by finger tip blood glucose monitoring in order to get the perfect self-monitoring method. Methods Totally 63 cases of type 1 and 2 diabetes mellitus were enrolled. The blood glucose values of those cases were monitored by CGMS for about(72±6)hours, and were proved by finger tip blood glucose monitoring about 4-7 times in all process. The finger tip blood glucose and dynamic blood glucose were tested for correlation. The values of mean blood glucose and the mean amplitude of glycemic excursions in 24 hours were calculated. At the same time, the points in(CGMS) monitoring process were picked, and then analyzed statistically to find suitable and economical self-monitoring points. Results 1 The mean blood glucose(MBG) values of "routine 8 points" and 7 points of "routine 8 points" had significant correlation with the 24 hours mean blood glucose(24hMBG) values. When the number of points was less than 7, the correlation decreased gradually with decreasing number of points. But there was significant correlation between 6 pionts and 5 points. 2 The mean amplitude of glycemic excursions(MAGE) values of "routine 8 time points" showed a close correlation with the 24 hours mean amplitude of glycemic excursions(24 h MAGE), and middling moderate correlation among 7, 6 and 5 points, and moderate correlation in before breakfast, after lunch, after supper, before sleep. Conclusion 1 The study on the mean blood glucose showed that "routine 8 points" and 7 points of "routine 8 points" could reflect adequately 24 hours mean blood glucose values. 2 The study on the mean amplitude of glycemic excursions showed that the routine 8 points could reflect the blood glucose fluctuation. It was proved that those points before breakfast, after lunch, after supper, before sleep had stronger effect on the blood glucose fluctuation.

Key words: diabetes mellitus, blood glucode fluctuation, self-monitoring