首都医科大学学报 ›› 2013, Vol. 34 ›› Issue (4): 492-493.doi: 10.3969/j.issn.1006-7795.2013.04.002

• 更年期及妇科内分泌 • 上一篇    下一篇

Progestogens and early pregnancy:prevention and treatment

Adolf E. Schindler   

  1. Institute for Medical Research and Education, Essen 45122, Germany
  • 收稿日期:2013-06-10 出版日期:2013-08-21 发布日期:2013-07-20

Progestogens and early pregnancy:prevention and treatment

Adolf E. Schindler   

  1. Institute for Medical Research and Education, Essen 45122, Germany
  • Received:2013-06-10 Online:2013-08-21 Published:2013-07-20

摘要:

During human and mammalian pregnancy, endogenous progesterone is the dominant hormone since it is not only essential for conception and implantation, but also needed throughout pregnancy. Progesterone provided the effects of prevention and treatment in human pregnancy by certain mechanisms. If one considers prevention or treatment with progestogens in human pregnancy, that all progestogens are progestogenic,if one condsiders the progestogens for prevention and therapeutic approaches, nowadays, only two progenstogens can be considered fully suitable for prevention and treatment in human pregnancy: progesterone and dydrogesteone. This review introduced the mechanism of progesterone and dydrogesterone in pregnancy and treatment in human.

关键词: progesterone, dydrogesteone, pregnancy

Abstract:

During human and mammalian pregnancy, endogenous progesterone is the dominant hormone since it is not only essential for conception and implantation, but also needed throughout pregnancy. Progesterone provided the effects of prevention and treatment in human pregnancy by certain mechanisms. If one considers prevention or treatment with progestogens in human pregnancy, that all progestogens are progestogenic,if one condsiders the progestogens for prevention and therapeutic approaches, nowadays, only two progenstogens can be considered fully suitable for prevention and treatment in human pregnancy: progesterone and dydrogesteone. This review introduced the mechanism of progesterone and dydrogesterone in pregnancy and treatment in human.

Key words: progesterone, dydrogesteone, pregnancy