关键词: 依托咪酯, 丙泊酚, 舒芬太尼, 人工流产术

Abstract:

Objective To compare the anesthesia effect of the etomidate or propofol combined with sufentanil used for artificial abortion. Methods Ninety-four cases of women in early pregnancy for induced abortion were randomly divided into two groups (Group E and Group B),with 47 patients in each group. After receiving 0.1 μg/kg sufentanil, patients in group E received 0.3 mg/kg etomidate and patients in group B received 2.0 mg/kg propofol.Blood pressure, heart rate and SPO₂ were monitored in the course of anesthesia. Operation time, wake-up time, recovery time of orientation, incidence of adverse reactions were observed in both groups. Results There was no significant difference between the two groups in age, weight, falling asleep time,operation time and wake up time. After injection, blood pressure was decreased significantly in group B (P<0.05) and it was stable in group E.The incidence of injection pain was 25.5% and 2.1% in group B and E respectively(P<0.01), The incidence of nausea was 2.1% in group B and 8.5% in group E. Conclusion Both etomidate and propofol can be used for artificial abortion anesthesia. Propofol induced a significant decrease of blood pressure and a higher incidence of injection pain. Etomidate maintained a stable blood pressure, but induced a higher incidence of myoclonus, nausea and nettle rash.

Key words: etomidate, propofol, sufentanil, artificial abortion