糖尿病患者听力损失的临床特点分析

doi:10.3969/j.issn.1006-7795.2015.01.016

首都医科大学学报 ›› 2015, Vol. 36 ›› Issue (1): 84-89.doi: 10.3969/j.issn.1006-7795.2015.01.016

• 糖尿病前期与神经病变 • 上一篇下一篇

糖尿病患者听力损失的临床特点分析

龚敬¹, 段金萍¹, 刘博¹, 杨毅², 周芸¹, 庄晓明³, 刘刚¹, 金昕⁴

1. 首都医科大学附属北京同仁医院耳鼻咽喉头颈外科北京市耳鼻咽喉科研究所教育部耳鼻咽喉头颈外科重点实验室, 北京 100730;
2. 首都医科大学附属北京同仁医院内分泌科, 北京 100730;
3. 首都医科大学附属复兴医院内分泌科, 北京 100038;
4. 中华耳鼻咽喉头颈外科杂志编辑部, 北京 100710

收稿日期:2014-09-01 出版日期:2015-02-21 发布日期:2015-01-31
通讯作者: 刘博, 金昕 E-mail:trliubo@139.com;jinxin@cma.org.cn
基金资助:
"十二五"国家科技支撑计划项目(2012BAI12B028);首都十大疾病科技成果推广项目(Z121107006212005).

Analysis of clinical characteristics of hearing loss in diabetes mellitus patients

Gong Jing¹, Duan Jinping¹, Liu Bo¹, Yang Yi², Zhou Yun¹, Zhuang Xiaoming³, Liu Gang¹, Jin Xin⁴

1. Department of Otorhinolaryngology, Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University; Beijing Institute of Otorhinolaryngology; Key Laboratory of Ministry of Education in Otorhinolaryngology Head and Neck Surgery, Beijing 100730, China;
2. Department of Endocrinology, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China;
3. Department of Endocrinology, Fuxing Hospital, Capital Medical University, Beijing 100038, China;
4. Editorial Office of Chinese Journal of Otorhinolaryngology Head and Neck Surgery, Beijing 100710, China

Received:2014-09-01 Online:2015-02-21 Published:2015-01-31
Supported by:
This study was supported by "Twelfth Five Year" National Science and Technology Support Program(2012BAI12B028); Capital Ten Major Disease Projects to Promote Scientific and Technological Achievements(Z121107006212005).

摘要/Abstract

摘要： 目的分析糖尿病患者与健康者听觉能力差异,探讨糖尿病患者听力损伤的影响因素.方法纳入2011年10月至2013年12月期间,在首都医科大学附属北京同仁医院内分泌科就诊并符合入组条件的2型糖尿病患者110例和无耳科疾病史,年龄与性别相匹配、无高血压、高血糖、高血脂的健康志愿者40例.通过问卷及纯音测听检查调查受试者听力状况.根据性别、年龄、糖尿病病程以及血糖控制水平分组.结果在被调查的110例糖尿病患者中:①31例主诉存在听力损失的患者纯音测听证实均有听力损失;而主诉听力正常的79例患者,有43例(54.4%)出现了不同程度听力损失.②糖尿病组各频率听阈均高于正常对照组,差异有统计学意义(P=0.000),且平均听力水平较正常对照组差,差异有统计学意义(P=0.000).③男性听力损失发病率(46/60,76.7%)高于女性(28/50,56%),差异有统计学意义(P=0.021);年龄40岁以上各年龄层的听力损失发病率(60%,60.5%,88.1%)明显高于年龄40岁以下各年龄层的发病率(16.7%,25%),差异有统计学意义(P=0.001).④糖尿病病程≥10年者听力损失发病率(45/56,80.4%)高于病程 < 5年者(16/29,55.2%)和5年≤病程<10年者(13/25,52.0%),差异有统计学意义(P=0.006).⑤ 不同血糖控制水平听力损失发病率的差异无统计学意义(P=0.465).结论糖尿病患者存在较高的听功能损伤风险.患者的主观感觉不能准确反映其听觉程度,无听力下降主诉的糖尿病患者中约1/2的人群存在听力下降.听力损失的发病率与糖尿病病程有关,与血糖控制水平无关.

关键词: 糖尿病, 听力损失, 影响因素

Abstract: Objective To analyze the differences of hearing function between diabetic and healthy patients, and investigate the factors which affect hearing among diabetics.Methods Questionnaires and pure tone audiometry were performed in 110 patients with type 2 diabetes mellitus who visited Beijing Tongren Hospital, Capital Medical University from October 2011 to December 2013, and compared with 40 age- and sex-matched controls. The patients were categorized into groups according to gender, age, duration of diabetes and glycemic control level. Results In all of the 110 subjects with diabetes, 31 cases complained of hearing loss, pure tone audiometry also confirmed the presence of hearing loss; while 79 cases had normal hearing, 43 cases (54.4%) of them experienced varying degrees of hearing loss. Hearing threshold in each frequency of diabetic group was significantly higher than the normal group, the difference was statistically significant (P=0.000). And the average hearing levels were significantly lower than those of the control group (P=0.000). The proportion of hearing loss for male (46 /60, 76.7%) was significantly higher than that of female (28/50, 56%, P=0.021);the proportion of subjects with hearing loss for all ages, those aged > 40 years (60%, 60.5%, 88.1%) were significantly higher than that of diabetics aged ≤ 40 years (16.7%, 25%, P=0.001). The prevalence of hearing loss for duration with diabetes ≥ 10 years (45/56, 80.4%) was significantly higher than those < 5 years (16/29, 55.2%) and 5≤those < 10 years (13/25, 52.0%, P=0.006). The differences of hearing loss in varied glycemic control levels were not statistically significant (P=0.465). Conclusion There is a higher risk of damage to auditory function in diabetic patients. The patient's subjective feeling does not reflect their hearing accurately. The occurrence of hearing loss is related with duration of diabetes regardless the level of glycemic control.

Key words: diabetes mellitus, hearing loss, relevant factors

中图分类号:

龚敬, 段金萍, 刘博, 杨毅, 周芸, 庄晓明, 刘刚, 金昕. 糖尿病患者听力损失的临床特点分析[J]. 首都医科大学学报, 2015, 36(1): 84-89.

Gong Jing, Duan Jinping, Liu Bo, Yang Yi, Zhou Yun, Zhuang Xiaoming, Liu Gang, Jin Xin. Analysis of clinical characteristics of hearing loss in diabetes mellitus patients[J]. Journal of Capital Medical University, 2015, 36(1): 84-89.

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糖尿病患者听力损失的临床特点分析

Analysis of clinical characteristics of hearing loss in diabetes mellitus patients

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