人卵巢组织冻存与移植研究进展

doi:10.3969/j.issn.1006-7795.2017.04.001

首都医科大学学报 ›› 2017, Vol. 38 ›› Issue (4): 485-491.doi: 10.3969/j.issn.1006-7795.2017.04.001

人卵巢组织冻存与移植研究进展

李扬璐¹, 阮祥燕^1,2, Alfred O. Mueck^1,2

1. 首都医科大学附属北京妇产医院内分泌科, 北京 100026;
2. 德国图宾根大学妇产医院内分泌与绝经中心, 图宾根 D-72076, 德国

收稿日期:2017-06-05 出版日期:2017-07-21 发布日期:2017-07-20
通讯作者: 阮祥燕 E-mail:ruanxiangyan@163.com
基金资助:
首都临床特色应用研究与成果推广（Z161100000516143），首都卫生发展科研专项项目（2016-2-2113），北京市医院管理局临床技术创新项目（XMLX201710），北京市卫生系统高层次卫生技术人才（学科带头人）（2014-2-016），国家外国专家局2017年度北京市引进国外技术、管理人才项目（20171100004）

Progress in human ovarian tissue cryopreservation and transplantation

Li Yanglu¹, Ruan Xiangyan^1,2, Alfred O. Mueck^1,2

1. Department of Gynecological Endocrinology, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing 100026, China;
2. Section of Endocrinology and Menopause, Department of Women's Health, University of Tubingen, Tubingen D-72076, Germany

Received:2017-06-05 Online:2017-07-21 Published:2017-07-20
Supported by:
This study was supported by Capital Characteristic Clinic Project of China(Z161100000516143); Beijing Capital Foundation for Medical Science Development and Research(2016-2-2113); Clinical Technique Innovation Project of Beijing Municipal Administration of Hospitals(XMLX201710); Beijing Municipality Health Technology High-level Talent(2014-2-016);Foreign Technical and Administrative Talent Introduction Project in 2017, State Administration of Foreign Experts Affairs of China(20171100004)

摘要/Abstract

摘要： 随着癌症治疗学的发展，癌症病人的生存率有了很大的提高。但性腺毒性治疗对肿瘤病人的生育力造成了不可逆的影响。有效的保护肿瘤病人的生育力，提高她们的生殖健康水平，是医疗工作者面临的重要问题。卵母细胞冻存、胚胎冻存、卵巢组织冻存等技术的发展是为女性生育力保护提供了可能。本文将简述目前常用的生育力保护方法，重点介绍人卵巢组织冻存与移植技术在生育力保护方面的重要作用。

关键词: 性腺毒性治疗, 生育力保护, 卵巢组织冻存与移植, 卵母细胞冻存, 胚胎冻存

Abstract: The survival rate of cancer patients is increasing with the development of cancer treatment methods. However, gonadotoxic therapies have an irreversible impact on ovarian function. Effective fertility protection and improving the level of reproductive health have become a crucial problem that health care providers confront. Improvements of oocyte and embryo cryopreservation, and ovarian tissue cryopreservation and transplantation provide feasible options for women's fertility protection. This review discusses the common fertility protection methods, focusing on the important role of human ovarian tissue cryopreservation and transplantation for fertility protection.

Key words: gonadotoxicity therapy, fertility protection, ovarian tissue cryopreservation and transplantation, oocyte cryopreservation, embryo cryopreservation

中图分类号:

R711.75

李扬璐, 阮祥燕, Alfred O. Mueck. 人卵巢组织冻存与移植研究进展[J]. 首都医科大学学报, 2017, 38(4): 485-491.

Li Yanglu, Ruan Xiangyan, Alfred O. Mueck. Progress in human ovarian tissue cryopreservation and transplantation[J]. Journal of Capital Medical University, 2017, 38(4): 485-491.

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人卵巢组织冻存与移植研究进展

Progress in human ovarian tissue cryopreservation and transplantation

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