室性期前收缩患者左室质量指数与早搏负荷、血尿酸的相关性分析

doi:10.3969/j.issn.1006-7795.2019.03.010

首都医科大学学报 ›› 2019, Vol. 40 ›› Issue (3): 374-378.doi: 10.3969/j.issn.1006-7795.2019.03.010

室性期前收缩患者左室质量指数与早搏负荷、血尿酸的相关性分析

罗鸿宇¹, 华琦², 刘荣坤²

1. 首都医科大学宣武医院老年病(综合)科, 北京 100053;
2. 首都医科大学宣武医院心内科, 北京 100053

收稿日期:2019-03-15 出版日期:2019-05-21 发布日期:2019-06-13
通讯作者: 华琦 E-mail:huaqi5371@sina.com
基金资助:
国家自然科学基金（8163001）。

Relationships between left ventricular myocardial mass index and PVC-burden and serum uric acid in patients with premature ventricular contractions

Luo Hongyu¹, Hua Qi², Liu Rongkun²

1. Department of Geriatric Medicine, Xuanwu Hospital, Capital Medical University, Beijing 100053, China;
2. Department of Cardiology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China

Received:2019-03-15 Online:2019-05-21 Published:2019-06-13
Supported by:
This study was supported by National Natural Science Foundation of China (8163001).

摘要/Abstract

摘要： 目的探讨室性期前收缩（premature ventricular complexes，PVCs）患者左室质量指数（left ventricular myocardial mass index，LVMI）与早搏负荷、血尿酸（serum uric acid，UA）的相关性。方法回顾性分析PVCs患者149例，根据LVMI水平分为单纯PVCs组（n=66）、PVCs合并左室肥厚（left ventricular hypertrophy，LVH）组（n=83），比较两组间早搏负荷、UA等参数的差异，并运用二元Logistic回归分析LVH的危险因素。结果与单纯PVCs组比较，PVCs合并LVH组早搏负荷、UA升高，差异有统计学意义（P<0.05）；二元Logistic回归分析提示年龄、早搏负荷、UA均为发生左心室肥厚的危险因素（P<0.05）。结论 PVCs患者LVMI与早搏负荷、UA相关，随PVCs加重，患者更易发生左室肥厚；对于早搏负荷重、尿酸升高的PVCs患者应监测心功能，及早予以干预。

关键词: 室性期前收缩, 左室质量指数, 左心室肥厚

Abstract: Objective To study the relationships between left ventricular myocardial mass index (LVMI) and PVC-burden and serum uric acid (UA) in patients with premature ventricular contractions(PVCs). Methods Totally 149 patients with PVCs were retrospectively analyzed. All the patients were divided into 2 groups with LVMI:the PVCs group (n=66) and the PVCs with left ventricular hypertrophy (LVH) group (n=83). The PVC-burden and UA level were compared and the Logistic regression analyses were used to identify the risk factors of LVH. Results Compared with the PVCs group, the PVC-burden and UA were increased in the PVCs with LVH group(P<0.05, respectively). In a binary Logistic regression analysis, age, PVC-burden and UA were the risk factors of LVH in patients with PVCs. Conclusion The LVMI was closely related to PVC-burden and UA. With the increase of PVCs burden, the patients with PVCs were prone to suffer LVH. For patients with a heavy load of PVC-burden and high level of UA, the cardiac function should be monitored on early stage and the clinical intervention should be provided in time.

Key words: premature ventricular complexes, left ventricular myocardial mass index, left ventricular hypertrophy

中图分类号:

R541.7

罗鸿宇, 华琦, 刘荣坤. 室性期前收缩患者左室质量指数与早搏负荷、血尿酸的相关性分析[J]. 首都医科大学学报, 2019, 40(3): 374-378.

Luo Hongyu, Hua Qi, Liu Rongkun. Relationships between left ventricular myocardial mass index and PVC-burden and serum uric acid in patients with premature ventricular contractions[J]. Journal of Capital Medical University, 2019, 40(3): 374-378.

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室性期前收缩患者左室质量指数与早搏负荷、血尿酸的相关性分析

Relationships between left ventricular myocardial mass index and PVC-burden and serum uric acid in patients with premature ventricular contractions

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