首都医科大学学报 ›› 2024, Vol. 45 ›› Issue (3): 548-555.doi: 10.3969/j.issn.1006-7795.2024.03.026

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嗜酸细胞性胃炎的研究进展

李中恕*   

  1. 北京大学人民医院消化内科,北京 100044
  • 收稿日期:2023-11-30 出版日期:2024-06-21 发布日期:2024-06-13

Understanding eosinophilic gastritis: new research insights

Li Zhongshu*   

  1. Department of Gastroenterology, Peking University Peoples Hospital, Beijing 100044, China
  • Received:2023-11-30 Online:2024-06-21 Published:2024-06-13

摘要: 嗜酸细胞性胃炎(eosinophilic gastritis,EoG)是临床少见疾病,近年发病率增加,发病机制尚不明确。该病临床及内镜下表现多样,缺乏特征性,目前尚无统一的诊断标准,临床医师及病理科医师提高对该病的警惕,是及早诊断并治疗的关键。近年生物制剂在该病的治疗中进展较快,但研究尚少;饮食消除、抑酸剂、糖皮质激素等常规的多种治疗在该病中的研究亦较少。嗜酸细胞性胃炎值得多方面的进一步研究。

关键词: 嗜酸细胞性胃炎, 发病机制, 临床表现, 治疗进展

Abstract: Eosinophilic gastritis (EoG) is an uncommon digestive disorder with an unclear cause. The prevalence of EoG has been on the rise in recent years. Clinically, EoG have no specific manifestations with most patients presenting with diverse features and endoscopic findings. There are no standardized diagnostic criteria for EoG as yet. Thus, vigilance among clinicians and pathologists is crucial for early diagnosis and treatment of EoG. While the use of biologics for EoG has witnessed significant advancements in recent years, there are few studies on this topic. Conventional treatments for EoG include food elimination diet, acid suppressants and glucocorticoids. Currently, research on standard therapeutic interventions is limited, which warrants further research to understand various aspects of EoG.

Key words: eosinophilic gastritis, pathogenesis, clinical manifestation, treatment advances

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