首都医科大学学报 ›› 2025, Vol. 46 ›› Issue (1): 125-129.doi: 10.3969/j.issn.1006-7795.2025.01.019

• 临床研究 • 上一篇    下一篇

亚健康脾气虚证与注意网络功能异常的关系

吴子遥1,2,  冯思同1,2*#,  贾竑晓1,2*#,  董麟瑞1,2,  宁艳哲1,2   

  1. 1.首都医科大学附属北京安定医院,国家精神心理疾病临床医学研究中心,精神疾病诊断与治疗北京市重点实验室,北京 100088;2.人脑保护高精尖创新中心,首都医科大学,北京  100069
  • 收稿日期:2024-11-11 出版日期:2025-02-21 发布日期:2025-02-25
  • 通讯作者: 冯思同,贾竑晓 E-mail:fengst1218@163.com; jhxlj@ccmu.edu.cn
  • 基金资助:
    国家自然科学基金项目(82174311),北京中医药薪火传承“新3+3”工程示范案例项目(2023-ZYSF-19)。

The relationship between sub-healthy individuals with spleen qi deficiency syndrome and attention network dysfunction

Wu Ziyao1,2, Feng Sitong1,2*#, Jia Hongxiao1,2*#, Dong Linrui1,2, Ning Yanzhe1,2   

  1. 1.The National Clinical Research Center for Mental Disorders & Beijing Key Laboratory of Mental Disorders, Beijing Anding Hospital, Capital Medical University, Beijing  100088, China; 2.Advanced Innovation Center for Human Brain Protection, Capital Medical University, Beijing  100069, China
  • Received:2024-11-11 Online:2025-02-21 Published:2025-02-25
  • Supported by:
    This study was supported by National Natural Science Foundation of China (82174311), Beijing Traditional Chinese Medicine Inheritance “New 3+3” Program Demonstration Case Project (2023-ZYSF-19). 

摘要: 目的  初步探究亚健康脾气虚证人群的注意网络功能。方法  2022年9月至2024年8月于社区和高校招募亚健康脾气虚证组受试者27例。根据年龄、性别和受教育年限相匹配纳入了25例健康对照受试者。对纳入的所有受试者进行注意网络测试,并分析两组差异。结果  相较于健康对照组,脾气虚证受试者的执行控制网络功能明显受损(P=0.012)。脾气虚证组和健康对照组的测试正确率、反应时间、警觉网络功能和定向网络功能差异均无统计学意义(P>0.05)。此外,脾气虚证组受试者健康状态简单评估问卷得分与执行控制网络效率值呈显著的负相关关系(P<0.001),脾气虚证证候积分与执行控制网络效率值呈正相关性(P=0.038)。结论  亚健康脾气虚证受试者的注意执行控制功能存在异常改变,其与脾气虚证症状的严重程度密切相关,这为“脾藏意”理论的认知心理学内涵提供了进一步的科学依据。

关键词: 脾气虚证, 亚健康, 认知, 注意网络, 脾藏意

Abstract: Objective  To explore the attentional network function in sub-healthy individuals with spleen qi deficiency syndrome.  Methods  Twenty-seven individuals in the sub-healthy spleen qi deficiency syndrome group were recruited from September 2022 to August 2024 in communities and colleges. Twenty-five healthy controls were also recruited according to the principle of matching age, gender, and years of education components. Attention network tests were performed on subjects in both groups. Results  Compared with the control group, the executive control network function value of the spleen qi deficiency syndrome group was significantly decreased (P=0.012). The differences in correct rate, overall reaction time, alert network and orientation network between the two groups were not statistically significant (P > 0.05). The results of correlation analysis showed a significant negative correlation between Health Evaluating Questionnaire  H20  V2009 scores and executive control network efficiency of the subjects in the spleen qi deficiency syndrome (P<0.001), and a positive correlation between the spleen qi deficiency syndrome score and executive control network efficiency (P=0.038). Conclusions  Abnormal changes in the executive control of attention in sub-healthy subjects with spleen qi deficiency syndrome were closely related to the severity of the symptoms of spleen qi deficiency, which provided further scientific evidence for the cognitive psychological connotation of the theory of “spleen stores Yi”.

Key words: spleen qi deficiency syndrome, sub-health, cognition, attention networks, spleen stores Yi

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