首都医科大学学报 ›› 1987, Vol. 8 ›› Issue (4): 283-285.

• 论著 • 上一篇    下一篇

原发性高血压患者红细胞膜Ca2+—ATP酶活性的初步观察

何士大1, 于仲元1, 张叔诚1, 刘成立2, 徐宝钢1, 汪家瑞1   

  1. 1. 首都医学院宣武医院心血管病研究室高血压实验室;2. 首都医学院宣武医院检验科
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:1987-10-15 发布日期:1987-10-15

The Preliminary Observation on the Activity of the Erythrocyte Membrane Ca2+ ATPase of Essential Hypertension Patients

He Shida1   

  1. Hypertension Lab, Cardiovascular Research Lab Xuanwu Hospital, Capital Institute of Medicine
  • Received:1900-01-01 Revised:1900-01-01 Online:1987-10-15 Published:1987-10-15

摘要: 细胞膜Ca2+—ATP酶对细胞内Ca2+转运发挥泵的作用。本文观察了20例原发性高血压患者红细胞膜Ca2+-ATP酶活性并与正常人比较,发现该酶话性明显低于正常人,提示高血压患者依赖ATP的Ca2+转运能力降低。并同时观察到高血压患者尿Ca2+排出量与正常人比较明显增加。

关键词: 原发性高血压, 红细胞膜, 钙-ATP酶

Abstract: The membrane Ca2+-ATPase has the function as the pump to transport the intracelluar Ca2+. This work observed the activity of thc erythrocytes membrane of 20 hypertension patients and 20 normal subjects.The results have showed that hypertension patients have the lower activity of erythrocytes membrane Ca2+-ATPase than the normal subjects。The urine Ca2+ excretion of hypertension patients is increaed significantly than the normal group.

Key words: essential hypertension, erythrocyte, membrane, Ca2+-ATPase