HBsAg携带者肝组织的免疫病理学研究

首都医科大学学报 ›› 1991, Vol. 12 ›› Issue (1): 19-22.

HBsAg携带者肝组织的免疫病理学研究

朱安¹, 谭承项², 李佩娟³

1. 首都医学院病理解剖学教研室;2. 北京医科大学病理解剖学教研室;3. 北京市儿童医院病理科

收稿日期:1990-03-02 修回日期:1900-01-01 出版日期:1991-01-15 发布日期:1991-01-15

The Immunopathologic Study of Liver Tissue of the HBsAg Carriers

Zhu An¹, Tan Chengxiang², Li Peijuan³

Department of Patho-anatomy, Capital Institute of Medicine

Received:1990-03-02 Revised:1900-01-01 Online:1991-01-15 Published:1991-01-15

摘要/Abstract

摘要： 应用免疫组织化学染色法从1668例尸检肝组织中检出HBsAg携带者(简称携带者)78例,检出率4.7%.以8～12岁及20～29岁组携带率较高.97例生前曾检测过血清HBsAg的病例中,血清、肝组织HBsAg均阳性者16例;血清阳性、肝组织阴性者1例;血清阴性、肝组织阳性者2例.携带者肝组织的病理变化:肝组织正常和非特异反应性炎占84.6%,慢性迁延性肝炎占7.7%,慢性活动性肝炎占2.6%,早期肝硬化占5.1%.本文中12岁以下携带者HBcAg阳性率明显高13岁以上携带者(P<0.025).

关键词: HBsAg 携带者, 肝组织, HBcAg

Abstract: 78 cases of asymptomatic HBsAg carriers were identified among 1668 cases of postmorem liver specimens by using immunohistochemical staining technique. The incidence was 4.7%,with the 8～12 years and the 20～29 years groups showing the highest positive rate.In 97 cases tested for serum HBsAg before death,16 cases showed HBsAg positive both in serum and in liver,2 cases were positive in liver but negative in serum,1 case was positive only in serum. Histopathological examination of 78 HBsAg carriers revealed that normal liver and NSRH were present in 84.6% of the carries,CPH was present in 7.7%, CAHwas present in 2.6%,the early stage of cirrhosis was present in 5.1%. The results also indicated that the incidence of HBcAg was significantly higher in children carriers than that in those who were elder than twelve (P<0.025).

Key words: HBsA gcarriers, liver tissue, HBcAg

朱安;谭承项;李佩娟. HBsAg携带者肝组织的免疫病理学研究[J]. 首都医科大学学报, 1991, 12(1): 19-22.

Zhu An;Tan Chengxiang;Li Peijuan. The Immunopathologic Study of Liver Tissue of the HBsAg Carriers[J]. Journal of Capital Medical University, 1991, 12(1): 19-22.