首都医科大学学报 ›› 1991, Vol. 12 ›› Issue (1): 23-26.

• 论著 • 上一篇    下一篇

家兔股动脉血栓形成模型及其形态学观察

陈铁军1, 陈瑞芬1, 常松1, 吴志敏1, 李楠2   

  1. 1. 首都医学院病理解剖学教研室;2. 首都医学院人体解剖学教研室
  • 收稿日期:1990-03-22 修回日期:1900-01-01 出版日期:1991-01-15 发布日期:1991-01-15

An Animal Model of the Femoral Artery Thrombosis in Rabbit and its Morphological Observations

Chen Tiejun1, Chen Ruifen1, Chang Jun1   

  1. Department of Patho-anatomy, Capital Institute of Medicine
  • Received:1990-03-22 Revised:1900-01-01 Online:1991-01-15 Published:1991-01-15

摘要: 根根据Virchow血栓形成原理,以家兔股动脉血管(直径1mm)制作血栓形成动物模型并在模型术后1~6d测量血栓体积,行股动脉造影、血小板计数检查及光镜下血栓组织学观察.结果显示:血栓体积在模型术后第4d最大,同时末梢血小板计数值也最高,以后随着血栓的明显机化,血栓体积趋于减小;血小板数值也相应减少至正常值范围。

关键词: 血栓, 血栓形成, 血栓模型

Abstract: An animal model of the femoral artery thrombosis based on virchows thrombosis principle was produced in rabbits.After the operations of the thrombosis model,we examined every thrombus volume and platelet quantity of every rabbit in the peripheral blood from the first to the sixth day.The radiography of the femoral artery and microscopic observations of the thrombi also were done.These results show the thrombus volume is the largest in the fourth day after the operations of the model.The platelet quantity is the highst in this time too.With the thrombns becoming organized its volume will be decreased and platelet quanlity will be ruduced to the normal level.

Key words: thrombus, thrombusis, animal model