首都医科大学学报 ›› 1992, Vol. 13 ›› Issue (1): 36-39.

• 论著 • 上一篇    下一篇

警惕脑内异体组织移植产生免疫排斥反应

贾保祥1, 刘玉军2, 张国风2, 曹家康3, 张茁3, 张瓦诚3   

  1. 1. 首都医学院附属北京友谊医院移植研究室;2. 首都医学院北京神经科学研究所;3. 首都医学院宣武医院
  • 收稿日期:1991-03-04 修回日期:1900-01-01 出版日期:1992-01-15 发布日期:1992-01-15

Paying Attention to Immunorejection in Intracephalic Transplantation

Jia Baoxiang1, Liu Yujun2, Zhang Guofeng2, Cao Jiakang3, Zhang Zhuo3, Zhang Wacheng3   

  1. 1. Department of transplantation, Beijing Friendship Hospital, Capital Institute of Medicine;2. Beijing Institute for Neuroscience, Capital Institute of Medicine;3. Department of Neurosury, Xuanwu Hospital, Capital Institute of Medicine
  • Received:1991-03-04 Revised:1900-01-01 Online:1992-01-15 Published:1992-01-15

摘要: 采用NIH标准补体依毫蔓的细胞毒法检测7例接受胚胎肾上腺髓质组织脑内移植患者血中抗T、B淋巴上的HLA-A、B、C、DR抗体。每1例患者血清对16名正常人T、B淋巴细胞进行微量细胞毒实验,结果1例患者血清呈HLA-DR抗体阳性反应。结果提示在开展胚胎组织脑内移植工作中应加强对免疫排斥反应的监视。

关键词: 移植, 胚胎, 肾上腺, 排斥反应

Abstract: The serum antibodies to HLA-A,B,C and DR which are on T and B lymphatic cells were examined by complement-depending standard method of NIH, which serum were tak-en from 7 patients who had received intracephalic transplantation of fetal adrenal medullary tissue.Every serum sample was mixed with T and B lymphocytes of 16 normal persons to perform micro-cytoxin reaction.The result presented postitive HLA-DR reaction in the serum from a patient.It showed that the rejection should be on regard in engaging intra-cephalic transplantation of fetal tissue clinically and should give more attention to immunore-jection.

Key words: transplantation, fetal, adrenal, rejection

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