枸杞提取液抗衰老作用的实验研究

首都医科大学学报 ›› 1992, Vol. 13 ›› Issue (2): 83-86.

枸杞提取液抗衰老作用的实验研究

王惠琴¹, 蒋保季¹, 马忠杰¹, 刘丽娟¹, 沈家芹¹, 张宏卫¹, 孔祥环², 唐玉萍², 赵淑珍², 肖忠新²

1. 首都医学院营养与食品卫生学教研室;2. 首都医学院环境卫生学教研室

收稿日期:1991-05-30 修回日期:1900-01-01 出版日期:1992-04-15 发布日期:1992-04-15

Experimental Study on the Antiaging Effect of Abstracted Juice of Lycium Chinense

Wang Huiqin¹, Jiang Baoji¹, Ma Zhongjie¹, Liu Lijuan¹, Shen Jiaqin¹, Zhang Hongwei¹, Kong Xianghuan², Tang Yuping², Zhao Shuzhen², Xiao Zhongxin²

1. Department of Nutrition and Food Hygiene, Capital Institute of Medicine;2. Department of Environmental Health, Capital Institute of Medicine

Received:1991-05-30 Revised:1900-01-01 Online:1992-04-15 Published:1992-04-15

摘要/Abstract

摘要： 采用体外试验、动物实验和人体试验的方法,研究了枸杞提取液的抗衰老作用。结果发现:枸杞提取液在试管内有明显抑制小鼠肝匀浆过氧化脂质(LPO)的生成作用,并呈剂量反应关系;小鼠体内试验证实可明显抑制肝LPO生成,并使血中谷胱甘肽过氧化物酶(GSH-Px)活力和红细胞超氧化物岐化酶(SOD)活力增高;人体试验显示可明显抑制血清LPO生成,使血中GSH-Px活力增高,但红细胞SOD活力未见升高。提示枸杞提取液具有抗衰老作用。

关键词: 抗衰老, 枸杞, 过氧化脂质, 超氧化物岐化酶, 谷胱甘肽过氧化物酶

Abstract: The antiaging effect of abstracted juice of lycium chinense in vitro and in vivo were studied. The result showed that the LPO product in homogeneous liver of mouse was inhi-bited by the juice in vitro with dose-response effect; The LPO product in liver of mouse de-creased significantly and the activity of SOD and GSH-Px in plasma of mouse increased sig-nificantly; The LPO product in plasma of old people decreased obviously and the activity of GSH-Px in plasma increased, but the activity of SOD decreased in old people. These results implied that the abstracted juice of lycium chinense has the obvious antiaging effect.

Key words: antiaging, lycium chinense, lipid peroxides, superoxide dismutase, glutathione peroxidase

中图分类号:

R285.5

王惠琴;蒋保季;马忠杰;刘丽娟;沈家芹;张宏卫;孔祥环;唐玉萍;赵淑珍;肖忠新. 枸杞提取液抗衰老作用的实验研究[J]. 首都医科大学学报, 1992, 13(2): 83-86.

Wang Huiqin;Jiang Baoji;Ma Zhongjie;Liu Lijuan;Shen Jiaqin;Zhang Hongwei;Kong Xianghuan;Tang Yuping;Zhao Shuzhen;Xiao Zhongxin. Experimental Study on the Antiaging Effect of Abstracted Juice of Lycium Chinense[J]. Journal of Capital Medical University, 1992, 13(2): 83-86.

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