首都医科大学学报 ›› 1994, Vol. 15 ›› Issue (1): 45-47.

• 论著 • 上一篇    下一篇

睾酮制剂对老年男性冠心病患者血浆心钠素水平的影响

吴赛珠, 翁心植   

  1. 首都医学院附属北京红十字朝阳医院内科
  • 收稿日期:1992-04-22 修回日期:1900-01-01 出版日期:1994-01-15 发布日期:1994-01-15

Effects of ANP Androgenic Preparation on Plasma Atrial Natriuretic Polypeptide Level in Elderly Male Coronary Heart Disease Patients

Wu Saizhu, Weng Xinzhi   

  1. Beijing Red-Cross Chaoyang Hospital, Capital Institute of Medicine
  • Received:1992-04-22 Revised:1900-01-01 Online:1994-01-15 Published:1994-01-15

摘要: 30例老年男性陈旧性心肌梗塞(OMI)患者,给予肌注长效睾酮制剂世代雄250.结果发现,用药后3周,患者血浆心钠素(ANP)及血清睾酮(T)水平明显上升(P均<0.01),雌二醇/睾酮(E2/T)比值下降(P<0.05).提示,世代雄250在改善老年男性OMI患者性激素代谢失衡的同时,还具有升高血浆ANP水平,弥补OMI患者ANP相对不足的作用.并对其机理进行了初步探讨.

关键词: 睾酮制剂, 心钠素, 陈旧性心肌梗塞, 性激素

Abstract: Thirty elderly men with old myocardial infarction(OMI)were treated with an androgenic preparation, sustanon 250. The result showed that plasma atrial natriuretic polypeptide(ANP)level and serum testosterone level were elevated significantly(both P<0.001)and estradial/testosterone(E2/T)ratio was reduced(P<0.05)after 3 weeks of sustanon 250 injections, indicating that sustanon 250 can elevate plasma ANP level and redemy relative ANP inadequacy, as well as improve sex hormone disorder in elderly men with OMI.

Key words: androgenic preparation, ANP, old myocardial infarction, sex hormone

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