壳多糖对创伤愈合作用的形态学观察

首都医科大学学报 ›› 1994, Vol. 15 ›› Issue (3): 176-179.

壳多糖对创伤愈合作用的形态学观察

陈瑞芬¹, 董晓黎¹, 张澄波², 郑国芬¹, 刘国贞¹

1. 首都医学院病理解剖学教研室;2. 首都医学院生物化学教研室

收稿日期:1994-07-02 修回日期:1900-01-01 出版日期:1994-07-15 发布日期:1994-07-15

Morphological Observation of Chitin in Wound Healing

Chen Ruifeng¹, Dong Xiaoli¹, Zhang Chenpou², Zheng Guofen¹, Liu Guozhen¹

1. Department of Pathology, Capital Institute of Medicine;2. Department of Biochemistry, Capital Institute of Medicine

Received:1994-07-02 Revised:1900-01-01 Online:1994-07-15 Published:1994-07-15

摘要/Abstract

摘要：

通过大白兔背部的创伤实验,对比观察了壳多糖对伤口愈合的作用.肉眼、光镜、电镜及免疫组化观察表明:壳多糖具有明显的诱导局部巨噬细胞增多、巨噬细胞吞噬能力增强、促进伤口收缩及愈合的作用;与云南白药组和空白对照组相比有显着差异.探讨了壳多糖促进伤口愈合的机理.

关键词: 壳多糖, 创伤愈合, 肉芽组织, 肌纤维母细胞

Abstract:

23 rabbites were wounded on the back.Each one had 3 wounds that were treated separately with chitin and Yunnan Baiyao.Microscopically,results showed woundtreated with chitin had more macrophages and myofibroblasts than those treated with Yunnan Baiyao and the empty control group Thus healing of wound was advanced and woundwas contracted.We sugest that myofibroblasts containing actin had the effect for wound contraction and the basal cells of squamous cell epithelium containing actin migrated toward the wound and finally covered the wound.

Key words: chitin, granulation tissue, myofibroblasts

中图分类号:

R392.1

陈瑞芬;董晓黎;张澄波;郑国芬;刘国贞. 壳多糖对创伤愈合作用的形态学观察[J]. 首都医科大学学报, 1994, 15(3): 176-179.

Chen Ruifeng;Dong Xiaoli;Zhang Chenpou;Zheng Guofen;Liu Guozhen. Morphological Observation of Chitin in Wound Healing[J]. Journal of Capital Medical University, 1994, 15(3): 176-179.

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