人参多糖和多抗甲素对动物红细胞变形能力的影响

首都医科大学学报 ›› 1995, Vol. 16 ›› Issue (3): 204-206.

人参多糖和多抗甲素对动物红细胞变形能力的影响

唐玉, 蔺桂芬

首都医学院药理学教研室

收稿日期:1994-06-03 修回日期:1900-01-01 出版日期:1995-07-15 发布日期:1995-07-15

The Effects of Ginseng Polysaccharides and Polyactin A on Erythrocyte Deformability in Rabbit and Rat

Tang Yu, Lin Guifen

Department of Pharmacology, Capital Institute of Medicine

Received:1994-06-03 Revised:1900-01-01 Online:1995-07-15 Published:1995-07-15

摘要/Abstract

摘要： 研究了人参多糖、多抗甲素经体内、体外给药对红细胞变形能力的影响。实验表明,人参多糖和多抗甲素均可改善红细胞的变形能力,使其滤过速度增快,与生理盐水组比较均有显着性差异(分别为P<0.01.P<0.05),提示应用人参多糖和多抗甲素对降低血液粘度,抑制血栓形成都有良好的效果。

关键词: 红细胞变形性, 人参多糖, 多抗甲素

Abstract: The effects of ginseng polysaccharides and polyactin A on erythrocyte deformability were studies in rabbits and rats. The results showed that ginseng polysaccharides and polyactin A could improve red-cell deformability. Comparing with the control group , there were remarkble differences in speed of filtration. In microcirculation, red cells can pass through those capillaries with diameters smaller than the red cells. This special ability plays an important role in microcirculation. The impaired erythrocyte deformability may increase the blood viscosity,decrease the volume of blood flow and lead to thrombosis. So,drugs that can raise the red cell deformability are effective for reducing blood viscosity and restraining thrombus formation.

Key words: erythrocyte deformability, ginseng polssaccharides, polyactin A

中图分类号:

R973

唐玉;蔺桂芬. 人参多糖和多抗甲素对动物红细胞变形能力的影响[J]. 首都医科大学学报, 1995, 16(3): 204-206.

Tang Yu;Lin Guifen. The Effects of Ginseng Polysaccharides and Polyactin A on Erythrocyte Deformability in Rabbit and Rat[J]. Journal of Capital Medical University, 1995, 16(3): 204-206.