几种常用肺结核病诊断方法临床价值的探讨

首都医科大学学报 ›› 1998, Vol. 19 ›› Issue (2): 133-135.

几种常用肺结核病诊断方法临床价值的探讨

张杰¹, 李玲², 张洪玉¹, 翁心植¹

1. 首都医科大学附属北京红十字朝阳医院呼吸科;2. 河北省复员军人医院呼吸科

收稿日期:1997-06-26 修回日期:1900-01-01 出版日期:1998-04-15 发布日期:1998-04-15

Study of Several Common Diagnostic Methods in Pulmonary Tuberculosis

Zhang Jie¹, Li Ling², Zhang Hongyu¹, Weng Xinzhi¹

Red Cross Chaoyang Hospital, Affiliate of Capital University of Medical Sciences

Received:1997-06-26 Revised:1900-01-01 Online:1998-04-15 Published:1998-04-15

摘要/Abstract

摘要： 为了探讨肺结核病的诊断方法,观察了直接痰涂片查抗酸杆菌、痰结核杆菌聚合酶链反应(PCR)检测法、结核菌素试验(PPD试验)和血中抗分枝杆菌抗体测定对肺结核病的诊断价值.结果表明:痰涂片法诊断肺结核病的特异性达100%,但敏感性只有22.2%.而其他3种方法虽然敏感性稍有提高,但特异性很差.提示:目前诊断肺结核病最可靠的方法仍是痰涂片法.

关键词: 肺结核, 直接痰涂片查抗酸杆菌, 聚合酶链反应, 结核菌素试验, 血中抗分枝杆菌抗体测定

Abstract: To explore the diagnostic method of pulmonary tuberculosis(PTB), the following methodsbacterial examination of tubercle bacill in sputum by acid fast staining technique was studied by smear acid fast staining technique(TB smear), polymerase chain reaction technique, PPD skin test and determination of antimycobacterial antibody level in the patient blood were utilized for diagnosing PTB. The results showed: The specificity of diagnosing PTB reached 100%, but the its sensitivity was very low(22.2%)by using TB smear. The other three methods were a little better in sensitivity, but were too bad in specificity. This suggested: The reliable diagnostic method of PTB is still a TB smear, however, the sensitivity is no good. The other three methods have limited value in diagnosing PTB.

Key words: pulmonary tuberculosis, TB smear, PCR, PPD, determination of antimycobacterial antibody level in the blood

中图分类号:

R521

张杰;李玲;张洪玉;翁心植. 几种常用肺结核病诊断方法临床价值的探讨[J]. 首都医科大学学报, 1998, 19(2): 133-135.

Zhang Jie;Li Ling;Zhang Hongyu;Weng Xinzhi. Study of Several Common Diagnostic Methods in Pulmonary Tuberculosis[J]. Journal of Capital Medical University, 1998, 19(2): 133-135.

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