首都医科大学学报 ›› 1998, Vol. 19 ›› Issue (3): 221-224.

• 论著 • 上一篇    下一篇

高血压病患者的收缩压和舒张压与左心功能相关关系的研究

华琦, 王西凤, 邢华, 李秀珍, 邢建刚   

  1. 首都医科大学宣武医院心血管内科
  • 收稿日期:1997-09-23 修回日期:1900-01-01 出版日期:1998-07-15 发布日期:1998-07-15

Correlation between Systolic and Diastolic Blood Pressure and Left Ventricular Systolic and Diastolic Function in Patients with Essential Hypertension

Hua Qi, Wang Xifeng, Xing Hua, Li Xiuzhen, Xing Jiangang   

  1. Cardiovascular Department, Xuanwu Hospital, Affiliate of Capital University of Medical Sciences
  • Received:1997-09-23 Revised:1900-01-01 Online:1998-07-15 Published:1998-07-15

摘要: 为了解收缩压(SBP)、舒张压(DBP)分别与左室收缩及舒张功能的相关关系,应用诊所血压及超声心动图方法观察374例高血压病患者。发现其收缩压与舒张早期充盈峰值流速(EPFV)呈明显负相关(P<0.05),与心房收缩期充盈峰值流速(APFV)及A/E比值呈明显正相关(P<0.05及0.01);舒张压与心输出量(CO)呈明显负相关(P<0.01),与舒张功能指标无相关关系。单纯性收缩期高血压组血清总胆固醇水平明显高于舒张期高血压组(P<0.001).多元逐步回归分析显示在排除众多因素以后,收缩压与A/E比值呈明显正相关(P<0.05),舒张压与年龄、CO呈明显负相关(P均<0.01).结果提示:高血压病患者收缩压主要影响左室舒张功能,舒张压主要影响左室收缩功能.

关键词: 高血压病, 超声心动描记术, 血压, 心脏功能试验

Abstract: To investigate the correlation between systolic and diastolic blood pressure and systolic and diastolic function of left ventricle, blood pressure and left ventricular function were observed by echocardiography in 374 patients with essential hypertension. It was found that there were negative correlation between systolic blood pressure(SBP)and peak flow velocity of early diastole(EPFV)(P<0.05), positive correlation between SBP and peak flow velocity of atrial contraction(APFV)(P<0.05)and between SBP and A/E(P<0.01); and there was negative correlation between diastolic blood pressure(DBP)and cardiac output(CO)(P<0.01). Cholesterol was higher in patients with isolated systolic hypertension than patients with diastolic hypertension(P<0.001). Stepwise multivariate regression analysis disclosed that A/E ratio all alone and jointly positively correlated with SBP, and age and CO all alone and jointly correlated with DBP. It was suggested that left ventricular diastolic function was mainly influenced by SBP and systolic function was mainly influenced by DBP.

Key words: essential hypertension, echocardiography, blood pressure, heart function test

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