首都医科大学学报 ›› 1998, Vol. 19 ›› Issue (3): 253-255.

• 论著 • 上一篇    下一篇

小剂量芬太尼和氟哌啶静注对吸入七氟醚快速麻醉诱导的影响

赵志丹, 庞杰, 李树人   

  1. 首都医科大学附属北京友谊医院麻醉科
  • 收稿日期:1997-09-20 修回日期:1900-01-01 出版日期:1998-07-15 发布日期:1998-07-15

Effect of Rapid Induction of Anesthesia with Inhalation of Sevoflurane before/after Intravenous Infusion of Low dose Fentanyl/droperidol

Zhao Zhidan, Pang Jie, Li Shuren   

  1. Department of Anesthesiology, Beijing Friendship Hospital, Affiliate of Capital University of Medical Sciences
  • Received:1997-09-20 Revised:1900-01-01 Online:1998-07-15 Published:1998-07-15

摘要: 为观察小剂量芬太尼和氟哌啶对吸入七氟醚快速麻醉诱导的影响。分别于吸入七氟醚后5min(第1组)和吸前2min(第2组)静注小剂量芬太尼(2μg/kg)及氟哌啶(0.1mg/kg).结果:病人意识消失时间第1组(87±37)s,第2组(39±11)s(P<0.01);深呼吸次数第1组(14.0±5.3)次;第2组(4.0±0.7)次(P<0.01).2组病人诱导及插管过程中循环反应相对较小。提示:在小剂量芬太尼及氟哌啶静注基础上吸入七氟醚继续行麻醉诱导其临床效果更佳,插管反应更小.

关键词: 七氟醚, 吸入诱导, 芬太尼, 氟哌啶

Abstract: To investigate the effect of rapid induction of anesthesia with inhalation of sevoflurane before/after intravenous infusion of low-dose fentanyl/droperidol.Sixteen ASA Ⅰ~Ⅱ patients under general anesthesia were randomly divided into two groups. In group 1: the 2 μg/kg fentanyl and 0.1 mg/kg droperidol were administrated intravenously during the 5 min after inhalation of sevoflurane, and in group 2: the 2 μg/kg fentanyl and 0.1 mg/kg droperidol were administered intravenously during the 2 min before induction.The results showed that the time necessary for loss of consciousness in group 1 and group 2 was(87±37)s,(39±11)s, and vital capacity breath frequency in group 1 and group 2 was 14.0±5.3, 4.0±0.7 respectively. Changes in blood pressure and heart rate were relatively small. The study shows that induction of anesthesia with inhalation of sevoflurane after intravenous infusion low dose fentanyl droperidol was found to be acceptable.

Key words: sevoflurane, inhalation induction, fentanyl, droperidol

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