首都医科大学学报 ›› 1999, Vol. 20 ›› Issue (2): 107-109.

• 论著 • 上一篇    下一篇

幽门螺杆菌阳性溃疡病的远期疗效观察

王瑶, 王雁, 袁申元, 万小平   

  1. 首都医科大学附属北京同仁医院消化内科
  • 收稿日期:1998-12-01 修回日期:1900-01-01 出版日期:1999-04-15 发布日期:1999-04-15

The Long-Term Observation of Duodenal Ulcer with Helicobacter Pylori

Wang Yao, Wang Yan, Yuan Shenyuan, Wan Xiaoping   

  1. Department of Gastroenterlogy, Beijing Tongren Hospital, Affiliate of Capital University of Medical Sciences
  • Received:1998-12-01 Revised:1900-01-01 Online:1999-04-15 Published:1999-04-15

摘要: 观察兰索拉唑联合2种抗生素与三钾双次枸橼酸络合铋单用治疗幽门螺杆菌阳性溃疡病的远期疗效。65例经尿素酶、组织学证实为幽门螺杆菌感染的病人,随机分为2组,三联治疗组(A组,35例)和三钾双次枸橼酸络合铋组(B组,30例).于疗程结束后1、6、12个月全部复查胃镜及13C呼气试验。结果:三联疗法幽门螺杆菌根除率高,溃疡病复发率低。

关键词: 幽门螺杆菌, 消化性溃疡, 兰索拉唑, 三钾双次枸橼酸络合铋, 远期观察

Abstract: In order to investigate the long-term curative effect of lansoprazole with other two antibiotics and bismuthi subcitras colloidal(De-Nol) respectively on duodenal ulcer. 65 DU patients with helicobacter pylori infection (urease test and histology for HP) were randomly divided into two groups. All of the patients were reexamined with gastroscopy and 13C-UBT in the 1th, 6th and 12th month after the therapeutic course. The eradication of HP was higher in lansoprazole with other two antibiotics than that of De-Nol, and the recurrence rates was very low.

Key words: helicobacter pylori, peptic ulcer, lansoprazole, De-Nol, longterm observation

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