咪唑安定和异丙酚复合全麻的临床观察

首都医科大学学报 ›› 1999, Vol. 20 ›› Issue (4): 282-284.

咪唑安定和异丙酚复合全麻的临床观察

冯忠, 赵志丹, 李树人

首都医科大学附属北京友谊医院麻醉科

收稿日期:1999-03-29 修回日期:1900-01-01 出版日期:1999-10-15 发布日期:1999-10-15

ClinicalStudy on Midazolam and Propofol Combined Anesthesia

Feng Zhong, Zhao Zhidan, Li Shuren

Department of Anesthesiology, Beijing Friendship Hospital, Affiliate of Capital University of Medical Sciences

Received:1999-03-29 Revised:1900-01-01 Online:1999-10-15 Published:1999-10-15

摘要/Abstract

摘要： 观察了咪唑安定(Ⅰ组)、异丙酚(Ⅱ组)和2药合用(Ⅲ组)对循环指标、应激反应及苏醒时间的影响。结果显示：Ⅰ、Ⅱ组麻醉诱导后SBP明显下降,Ⅲ组变化不明显。麻醉维持期循环稳定。意识恢复时间Ⅱ组(5～13min)和Ⅲ组(7～20min)相近,Ⅰ组最长(35～80min).Ⅰ组术中血管紧张素Ⅱ及醛固酮较麻醉前明显升高(P<0.05),Ⅱ、Ⅲ组则相对稳定。提示：咪唑安定与异丙酚合用不仅有协同作用,且可取长补短,属临床可供选用的麻醉方法之一。

关键词: 咪唑安定, 异丙酚, 应激反应

Abstract: In order to investigate the effects of midazolam only (Ⅰgroup) 、propofol only (Ⅱ group) and midazolam combined with propofol (Ⅲgroup) on circulation ,stress and awakening time.Afterinduction SBPdecreased significantly in Ⅰand Ⅱgroups,butthere was no remarkable changein Ⅲgroup.The circulation was stable during anesthesia maintenance.Ⅱand Ⅲgroups had approximate awakening time (Ⅱgroup 5 ～13 min, Ⅲgroup 7 ～20 min) and Ⅰgroup was 35 ～80 min.Angitensin Ⅱand aldosteronelevels changed greatly than pre anesthesiai,but there was only little change in Ⅱand Ⅲgroups.Midazolam combined with propofol not only had cooperated effects but also could overcome each defect.It was a selectable anesthesia method for clinical use.

Key words: midazolam, propofol, stress

中图分类号:

R614.2

冯忠;赵志丹;李树人. 咪唑安定和异丙酚复合全麻的临床观察[J]. 首都医科大学学报, 1999, 20(4): 282-284.

Feng Zhong;Zhao Zhidan;Li Shuren. ClinicalStudy on Midazolam and Propofol Combined Anesthesia[J]. Journal of Capital Medical University, 1999, 20(4): 282-284.

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