药物流产出血者刮宫组织中孕酮受体的表达

首都医科大学学报 ›› 2002, Vol. 23 ›› Issue (2): 105-106.

药物流产出血者刮宫组织中孕酮受体的表达

梁元晶¹, 许晴¹, 诸定寿¹, 房敬燕²

1. 首都医科大学解剖学系;2. 首都医科大学宣武医院妇产科

收稿日期:2001-09-13 修回日期:1900-01-01 出版日期:2002-04-15 发布日期:2002-04-15

Study of Progesterone Receptor in Extracted Tissue after Mifepristone Induced Abortion

Liang Yuanjing¹, Xu Qing¹, Zhu Dingshou¹, Fang Jingyan ²

1. Department of Anatomy, Capital University of Medical Sciences;2. Department of Obstetrics and Gynecology, Xuanwu Hospital, Affiliate of Capital University of Medical Sciences

Received:2001-09-13 Revised:1900-01-01 Online:2002-04-15 Published:2002-04-15

摘要/Abstract

摘要： 为研究孕酮受体(PR)与米非司酮抗早孕出血残留蜕膜和绒毛的关系,用免疫细胞化学LSAB法显示出血后刮出组织(19例)中的PR.发现PR在子宫内膜基质细胞、腺上皮细胞、肌上皮细胞、血管内皮细胞和平滑肌细胞多呈阳性或强阳性,在残留绒毛呈弱阳性,而在残留蜕膜细胞多为阴性。PR在子宫内膜和残留蜕膜中的分布有显着性差异(P<0.01).提示药流后蜕膜和绒毛残留与蜕膜中孕酮受体无关,而内膜中孕酮受体的作用有待进一步研究。

关键词: 孕酮受体, 米非司酮抗早孕, 免疫细胞化学

Abstract: It is reported that remaining decidua and villi are found in the uterus of some patients who have uterogenic bleeding after mifepristone induced abortion. The purpose was to study the expression of progesterone receptor(PR)in these remaining tissues(n=19)by immunocytochemical LSAB methods. PR was mainly distributed in glandular epithelium, peripheral musculodermic cells, endometrial stroma cells, vesicular endothelium and musclar cells in uterus. These tissue showed positive or strong positive. The remaining chorion villi showed weak positive. Decidual showed negative, despite a few positive cells that were extra-chorion trophoblast and vescular endothelium. PR in the endometrium and decidua were significantly different(P<0.01). This study indicates that the residue of decidua and villi after mifepristone induced abortion are not caused by PR in these tissues.

Key words: progesterone receptor|mifepristone induced abortion|immunocytochemistry

中图分类号:

R714.22

梁元晶;许晴;诸定寿;房敬燕. 药物流产出血者刮宫组织中孕酮受体的表达[J]. 首都医科大学学报, 2002, 23(2): 105-106.

Liang Yuanjing;Xu Qing;Zhu Dingshou;Fang Jingyan . Study of Progesterone Receptor in Extracted Tissue after Mifepristone Induced Abortion[J]. Journal of Capital Medical University, 2002, 23(2): 105-106.

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