关键词: 创伤, 弥散性血管内凝血, 治疗, 肝素

Abstract: To investigate the clinical and experimental features of trauma complicated with disseminated intravascular coagulation(DIC)and to improve the level of diagnosis and treatment to trauma complicated with DIC, 36 cases of trauma complicated with DIC from 1980 to 1998 were analysed. All the cases were severely injuried, among which 4 cases were in early stage of DIC and 32 cases were in late stage; 28 cases complicated with infections, 25 with shock and 10 with ARDS. The primary clinical features were repetitive and multiple hemorrhage in the whole body, refractory shock or multiple organ malfunction. All the cases showed the progressive reduction of Plt, prolongation of PT and 3P positive. Twenty- five cases were treated with low-dose heparin, 9 of the 25 cases died, the morality was 36%. The most important predisposing factors leading to DIC in severe trauma are infection and shock. The continuous reduction of Plt, prolongation of PT and positive of 3P are important to the diagnosis of DIC. ARDS incidence is high in traumatic DIC. The use of low-dose heparin may improve the treatment result.

Key words: trauma|disseminative intravascular coagulation(DIC)|treatment|heparin