首都医科大学学报 ›› 2005, Vol. 26 ›› Issue (2): 187-189.

• 论著·临床研究 • 上一篇    下一篇

儿童下丘脑区肿瘤术后钠代谢的变化

李德志, 王忠诚, 刘颖, 张玉琪, 马振宇   

  1. 首都医科大学北京市神经外科研究所
  • 收稿日期:2004-01-30 修回日期:1900-01-01 出版日期:2005-04-24 发布日期:2005-04-24

Disorders of Serum Sodium among Children after Hypothalamus Tumors Operations

Li Dezhi, Wang Zhongcheng, Liu Ying, Zhang Yuqi, Ma Zhenyu   

  1. Beijing Neurosurgery Institute, Capital University of Medical Sciences
  • Received:2004-01-30 Revised:1900-01-01 Online:2005-04-24 Published:2005-04-24

摘要:

目的 探讨儿童下丘脑区肿瘤术后钠代谢的变化规律和特点。方法 对24例鞍区三脑室肿瘤患儿于术前、术后每日检测血电解质,留取24h尿检测尿钠;检测高血钠或低血钠高峰时的血清晶体渗透压。结果 24例患儿术后血钠正常者4例,单纯高血钠者6例,单纯低血钠者8例,6例患儿既出现高血钠又出现低血钠。术后高血钠时血清晶体渗透压较术前显著升高,24h尿钠较术前显著降低;而术后低血钠时血清晶体渗透压较术前显著降低,24h尿钠较术前显著升高。结论 儿童下丘脑区肿瘤术后血钠紊乱多见,血钠改变与尿钠的变化密切相关,高钠血症时尿钠排出减少,而低钠血症的钠代谢特点为高尿钠、低血钠。

关键词: 鞍区, 三脑室, 术后, 高钠血症, 低钠血症, 儿童

Abstract:

Objective To analyze characteristics of the disorders of serum sodium among children after tumors operations in the hypothalamus region. Methods 24 children with the tumor in this region were studied. The electrolyte and the sodium in 24h urine were measured everyday before and after operation. The crystal osmotic pressures of serum were analyzed at the peak of serum sodium change. Results 4 children had normal serum sodium among the 24 Cases, 6 with hypernatremia, 8 with hyponatremia and 6 with both high and low serum sodium. In hypernatremia cases, the crystal osmotic pressure of serum increased and the urine sodium reduced sharply after operation compared with that of before operation. In hyponatremia cases, the crystal osmotic pressure of serum reduced and the urine sodium increased more significantly after operation than those of before operation. Conclusion The disorders of serum sodium among children after tumors operations in the hypothalamus region were common. The disorders of serum sodium were related to the changes of urine sodium. Hypernatremia is characterized by decreased urine sodium secretion. Hyponatremia is characterized by decreased serum sodium and increased urine sodium secretion.

Key words: seller region, the third ventricle, after operation, hypernatremia, hyponatremia, children

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