蜂胶对变形链球菌产酸的影响

首都医科大学学报 ›› 2006, Vol. 27 ›› Issue (3): 302-303.

蜂胶对变形链球菌产酸的影响

王晶, 李玉晶, 葛丽华, 杨冬梅

首都医科大学附属北京口腔医院牙体牙髓科

收稿日期:2005-11-30 修回日期:1900-01-01 出版日期:2006-06-24 发布日期:2006-06-24
通讯作者: 李玉晶

Investigation of the Effect of Propolis on the Production of Lactic Acid from S. Mutans

Wang Jing, Li Yujing, Ge Lihua, Yang Dongmei

Department of Endodontics, Beijing Stomatology Hospital, Capital University of Medical Sciences

Received:2005-11-30 Revised:1900-01-01 Online:2006-06-24 Published:2006-06-24

摘要/Abstract

摘要： 目的探讨北京蜂胶提取物对变形链球菌产酸的影响.方法以TPY液体培养基为溶剂,分别配制5 g/L和1.25g/L水溶性蜂胶溶液,1.562 5 g/L醇溶性蜂胶溶液,1.6 g/L洗必泰液体培养基,并以空白液体培养基作为对照,加入变形链球菌培养48 h后离心,用乳酸分析仪测定培养基中乳酸含量并进行比较.结果醇溶性蜂胶溶液和水溶性蜂胶溶液皆可使乳酸值降低,蜂胶各组与对照组相比差异均有统计学意义(P＜0.05).5 g/L水溶性蜂胶溶液降低乳酸值的作用明显大于1.25 g/L水溶性蜂胶溶液(P＜0.05).醇溶性蜂胶溶液和5 g/L水溶性蜂胶溶液与洗必泰3组降低乳酸值的作用比较差异均无统计学意义(P＞0.05).结论北京蜂胶提取物影响变形链球菌的代谢,使变形链球菌代谢产酸减少.

关键词: 蜂胶, 变形链球菌, 产酸

Abstract: Objective To study the effect of proplis on the production of lactic acid from S.Mutans.Methods S.mutans and S.sobrinus were inoculated into the TPY culture mediums which contained 5 g/L or 1.25 g/L proplis extract in water, 1.562 5 g/L proplis extract in ethanol, chlorhexidine, and TPY culture medium as control group respectively. Having been cultured for 48 h, the lactic acid in each solution was examined and compared.Results There was no statistic difference between the groups of 5 g/L proplis extract in water, 1.562 5 g/L proplis extract in ethanol, and chlorhexidine, whereas the statsitc difference between the above three groups and the control group were significant, and there was also a significant difference between the 1.25 g/L proplis extract in water group and both chlorhexidine and control group.Conclusion similar to chlorhexidine, Beijing proplis extracts in water and ethanol apparently inhibit the lactic acid production by S. mutans and S. sobrinus.

Key words: proplis, S. mutans, acid

中图分类号:

R781.4

王晶;李玉晶;葛丽华;杨冬梅. 蜂胶对变形链球菌产酸的影响[J]. 首都医科大学学报, 2006, 27(3): 302-303.

Wang Jing;Li Yujing;Ge Lihua;Yang Dongmei . Investigation of the Effect of Propolis on the Production of Lactic Acid from S. Mutans[J]. Journal of Capital Medical University, 2006, 27(3): 302-303.

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