健脾消胀制剂对大鼠胃电-机械活动的影响

首都医科大学学报 ›› 2006, Vol. 27 ›› Issue (3): 329-331.

健脾消胀制剂对大鼠胃电-机械活动的影响

张知非¹, 王伟¹, 刘汶², 曲瑞瑶¹, 童学红¹, 崔茜¹

1. 首都医科大学生理学教研室;2. 首都医科大学附属北京中医医院

收稿日期:2005-06-16 修回日期:1900-01-01 出版日期:2006-06-24 发布日期:2006-06-24
通讯作者: 王伟

Effects of Jianpi Xiaozhang Supplement on Gastric Electro-mechanical Activity in Rats

Zhang Zhifei¹, Wang Wei¹, Liu Wen², Qu Ruiyao¹, Tong Xuehong¹, Cui Qian¹

1. Department of Physiology, Capital University of Medical Sciences;2. Beijing TCM Hospital, Capital University of Medical Sciences

Received:2005-06-16 Revised:1900-01-01 Online:2006-06-24 Published:2006-06-24

摘要/Abstract

摘要： 目的观察健脾消胀制剂对大鼠胃运动的影响.方法采用胃饲树脂小球并计数的方法计算胃排空率,采用高灵敏度感应片传感器记录在体胃在用不同剂量的健脾消胀制剂前后的运动改变.结果高、中、低剂量(5 g/kg、2 g/kg和0.5 g/kg)健脾消胀制剂组的胃排空率均显著快于对照组(P＜0.001,P＜0.001,P＜0.05).高、中、低剂量的健脾消胀制剂均使胃运动幅度和胃电慢波振幅增加.结论健脾消胀制剂能增强胃电-机械运动,且呈剂量依赖性.

关键词: 胃电-机械活动, 健脾消胀制剂, 胃排空率, 胃运动

Abstract: Objective To study the effects of Jianpi Xiaozhang supplement on electro-mechanical activity in rat.Methods Colophony globules were administered to rats by gastrogavage and the gastric emptying rate was calculated by counting the number of colophony globules in stomach. The movements of stomach before and after gastrogavage were recording by using high sensitive stress plate transducer.Results The gastric emptying rates in rats administered with Jianpi Xiaozhang supplement in the dose of (5 g/kg, 2 g/kg and 0.5 g/kg) were quicker than that in control group(P<0.001,P<0.001,P<0.05). Jianpi Xiaozhang supplement in the dose of (5 g/kg, 2 g/kg and 0.5 g/kg)increased markedly the average amplitude of gastric movement and gastric slow wave.Conclusion Jianpi Xiaozhang supplement dose-relatedly enhanced gastric electro-mechanical activity.

Key words: gastric electro-mechanical activity, Jianpi Xiaozhang supplement, gastric emptying rate, gastric movement

中图分类号:

R285

张知非;王伟;刘汶;曲瑞瑶;童学红;崔茜. 健脾消胀制剂对大鼠胃电-机械活动的影响[J]. 首都医科大学学报, 2006, 27(3): 329-331.

Zhang Zhifei;Wang Wei;Liu Wen;Qu Ruiyao;Tong Xuehong;Cui Qian. Effects of Jianpi Xiaozhang Supplement on Gastric Electro-mechanical Activity in Rats[J]. Journal of Capital Medical University, 2006, 27(3): 329-331.

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