颅内生殖细胞瘤诊断性放疗剂量的初步探讨

首都医科大学学报 ›› 2006, Vol. 27 ›› Issue (3): 395-396.

颅内生殖细胞瘤诊断性放疗剂量的初步探讨

邱晓光¹, 罗世祺¹, 马振宇¹, 张玉琪¹, 甲戈¹, 王明明², 李守巍³

1. 首都医科大学附属北京天坛医院放射治疗科;2. 北京市普仁医院;3. 哈尔滨医科大学第一临床医院

收稿日期:2005-08-29 修回日期:1900-01-01 出版日期:2006-06-24 发布日期:2006-06-24

Preliminary Dosage Research on Diagnostic Radiation of Intracranial Germinoma

Qiu Xiaoguang¹, Luo Shiqi¹, Ma Zhenyu¹, Zhang Yuqi¹, Jia Ge¹, Wang Mingming², Li Shouwei³

1. Department of Roentgenology, Beijing Tiantan Hospital, Capital University of Medical Sciences;2. Beijing Puren Hospital;3. The First Hospital of Harbin Medical University

Received:2005-08-29 Revised:1900-01-01 Online:2006-06-24 Published:2006-06-24

摘要/Abstract

摘要： 目的探索颅内生殖细胞瘤诊断性放疗最低有效剂量,减少患者的无谓照射.方法回顾性分析了经放疗证实的生殖细胞瘤患者75例共104个病灶(其中单发病灶者51例,2个病灶者19例,3个病灶者5例),观察应用10 Gy和20 Gy的照射剂量时,病灶反应数目的变化.结果 2种实验性放射疗法剂量对肿瘤病灶数目的影响未见显著性差异.结论在颅内生殖细胞瘤的诊断性放射疗法中,10 Gy可作为排除部分非生殖细胞瘤的初步剂量.

关键词: 非生殖细胞瘤性生殖细胞肿瘤, 生殖细胞瘤, 诊断性放疗, 放射疗法

Abstract: Objective To evaluate the minimum dosage of efficiency in diagnostic radiation for intracranial germinoma to reduce the patients' unnecessary radiation.Methods Retrospective analysis were performed in 75 germinoma patients with 104 lesions totally that were clinically verified by radiotherapy, including 51 patients with single lesion, 19 patients with two lesions and 5 patients with three lesions. The response case number were analyzed by chi-squire examination at the radiation dosage of 10 Gy and 20 Gy.Results Statistical analysis showed no difference in the number of responsive patients between 10 Gy and 20 Gy radiation dosage.Conclusion For intracranial germinoma, 10 Gy is the preliminary minimum dosage of diagnostic radiation to confirm the suspected germinoma.

Key words: non-germinoma germ cell tumors, germinoma, diagnostic radiation, radiotherapy

中图分类号:

R739.41

邱晓光;罗世祺;马振宇;张玉琪;甲戈;王明明;李守巍. 颅内生殖细胞瘤诊断性放疗剂量的初步探讨[J]. 首都医科大学学报, 2006, 27(3): 395-396.

Qiu Xiaoguang;Luo Shiqi;Ma Zhenyu;Zhang Yuqi;Jia Ge;Wang Mingming;Li Shouwei. Preliminary Dosage Research on Diagnostic Radiation of Intracranial Germinoma[J]. Journal of Capital Medical University, 2006, 27(3): 395-396.