曲安奈德联合玻璃酸钠注射液治疗骨性膝关节炎的疗效观察

首都医科大学学报 ›› 2006, Vol. 27 ›› Issue (6): 830-832.

曲安奈德联合玻璃酸钠注射液治疗骨性膝关节炎的疗效观察

王前¹, 倪家骧², 史京哲²

1. 首都医科大学宣武医院麻醉科;2. 首都医科大学宣武医院疼痛诊疗中心

收稿日期:2006-06-16 修回日期:1900-01-01 出版日期:2006-12-24 发布日期:2006-12-24

Efficacy of Intra-articular Triamcinolone Acetonide and Sodium Hyaluronic in the Treatment of Knee Osteoarthritis

Wang Qian¹, Ni Jiaxiang², Shi Jingzhe²

1. Department of Anesthesiology, Xuanwu Hospital, Capital University of Medical Sciences;2. Pain Center, Xuanwu Hospital, Capital University of Medical Sciences

Received:2006-06-16 Revised:1900-01-01 Online:2006-12-24 Published:2006-12-24

摘要/Abstract

摘要： 目的观察曲安奈德联合玻璃酸钠关节腔内注射治疗骨性膝关节炎的疗效.方法选择36例骨性膝关节炎的患者,关节腔内和周围痛点注射曲安奈德,每周1次,共2次.2周后周围痛点治疗不变,关节腔内注入玻璃酸钠注射液,每周1次,共5次.采用Lysholm膝关节功能评分标准进行评分,比较治疗前、治疗后1周和治疗后3个月膝关节功能评分结果.结果治疗后1周和治疗后3个月Lysholm膝关节功能评分显著高于治疗前.结论曲安奈德联合玻璃酸钠注射液关节腔内注射可以明显改善骨性膝关节炎的临床症状,远期效果良好.

关键词: 皮质类固醇, 玻璃酸钠, 骨性膝关节炎, 关节腔内注射

Abstract: Objective To observe the efficacy of treatment using intra-articular triamcinolone acetonide and sodium hyaluronic in patients with knee osteoarthritis.Methods 36 patients with knee osteoarthritis were enrolled in this study.All the patients received intra-articular and trigger point injections of triamcinolone acetonide once a week for 2 consecutive weeks then intracavitary injections of sodium hyaluronic for 5 times with one-week intervals and trigger point injections are as before.Lysholm Knee Scale scores were recorded at baseline,at week 1and at months 3.Results The Lysholm Knee Scale scores at week 1 and at months 3 were significantly higher than that at baseline.Conclusion Intra-articular triamcinolone acetonide and sodium hyaluronic provide clinically significant improvement and a long-term beneficial effects in patients with knee osteoarthritis.

Key words: corticosteroid, sodium hyaluronate, osteoarthritis, intra-articular injection

中图分类号:

R684.3

王前;倪家骧;史京哲. 曲安奈德联合玻璃酸钠注射液治疗骨性膝关节炎的疗效观察[J]. 首都医科大学学报, 2006, 27(6): 830-832.

Wang Qian;Ni Jiaxiang;Shi Jingzhe. Efficacy of Intra-articular Triamcinolone Acetonide and Sodium Hyaluronic in the Treatment of Knee Osteoarthritis[J]. Journal of Capital Medical University, 2006, 27(6): 830-832.