hPET与CT联合应用在支气管肺癌诊断中的作用

首都医科大学学报 ›› 2008, Vol. 29 ›› Issue (1): 26-28.

hPET与CT联合应用在支气管肺癌诊断中的作用

李春林¹, 杨吉刚¹, 马大庆², 龚民³, 邹兰芳¹

1. 首都医科大学附属北京友谊医院核医学科;2. 首都医科大学附属北京友谊医院放射科;3. 首都医科大学附属北京友谊医院胸外科

收稿日期:2007-11-18 修回日期:1900-01-01 出版日期:2008-02-24 发布日期:2013-07-15
通讯作者: 杨吉刚

Application of hPET and CT in Combination of Detection of Bronchogenic Carcinoma

Li Chunlin¹, Yang Jigang¹, Ma Daqing², Gong Min³, Zou Lanfang¹

1. Department of Nuclear Medicine, Beijing Friendship Hospital, Capital Medical University;2. Department of Radiology, Beijing Friendship Hospital, Capital Medical University;3. Department of Thoracic Surgery, Beijing Friendship Hospital, Capital Medical University

Received:2007-11-18 Revised:1900-01-01 Online:2008-02-24 Published:2013-07-15

摘要/Abstract

摘要： 目的评价hPET(hybrid PET)与CT及hPET与CT联合应用在支气管肺癌诊断中的价值.方法对192例临床怀疑肺癌的患者在手术前完成hPET及CT 2种检查.对肺部病变的¹⁸F-FDG浓聚程度及特征进行分析,以局部斑块状放射性异常浓聚灶为阳性(肺癌),以无明显放射性浓聚或浓聚呈云片状、散在性模糊的影像为阴性(良性).肺部肿块有肺癌CT阳性征象,即认为阳性(肺癌),反之则认为阴性(良性).结果病理学检测证实145例患者为肺癌,47例为肺部良性病变.hPET假阴性率和假阳性率分别为49.0%和12.1%;CT假阴性率和假阳性率分别为50.9%和9.5%,hPET+CT假阴性率和假阳性率分别为17.8%和7.6%.CT诊断结果与病理学检测结果不符合者41例,占21.4%.在这41例患者中,hPET结果与病理学检测结果符合者24例,占58.5%.单独应用CT者符合率为78.65%,单独应用hPET者符合率为78.13%;CT与hPET联合应用总符合率为91.15%,与前两者相比差异有统计学意义.结论分别单独应用hPET和CT在支气管肺癌诊断的假阴性率和假阳性率之间差异无统计学意义,但二者联合应用可以提高支气管肺癌的诊断准确率.

关键词: 肺部肿块, hPET, CT

Abstract: Objective To evaluate the diagnostic value of hPET and CT in bronchogenic carcinoma and the application of hPET and CT in combination.Methods One hundred and ninety-two inpatients with suspected lung malignancy had hPET and CT examinations which were completed before surgery.All images were analyzed visually.It was considered positive for malignancy if the ¹⁸F-FDG uptake was increased relative to that in the adjacent lung tissue and the uptake of ¹⁸F-FDG was focal.Otherwise,it was considered negative if the ¹⁸F-FDG uptake was increased in a sheet form and the margin of the uptake was blurred.If the lung lesions had positive CT signs,they were considered as malignancy.Otherwise,they were considered benign.Results One hundred and forty-five patients were proven to have lung cancer by pathology,and 47 patients had benign lung diseases.The false-negative and false-positive rates of hPET was 49.0% and 12.1%.The false-negative and false-positive of rates CT was 50.9% and 9.5%.The false-negative and false-positive of hPET combination of CT is 17.8% and 7.6%.There were no significant differences between false-positive and false-negative rates of hPET and CT.The CT results of 41 patients(21.4%) were falsely contrasted with pathological results,but hPET results of 24 patients(58.5%) were identical with pathological results.The coincidence rates of single CT or hPET with pathological results were 78.65% and 78.13%,respectively.The coincidence rate of combined application of hPET and CT with pathological results was 91.15%.Conclusion There are no significant differences of false-positive and false-negative results between single hPET and CT,but combined application of hPET and CT can improve the correct diagnosis rate of lung lesions.

Key words: lung lesions, hPET, CT

中图分类号:

李春林;杨吉刚;马大庆;龚民;邹兰芳. hPET与CT联合应用在支气管肺癌诊断中的作用[J]. 首都医科大学学报, 2008, 29(1): 26-28.

Li Chunlin;Yang Jigang;Ma Daqing;Gong Min;Zou Lanfang. Application of hPET and CT in Combination of Detection of Bronchogenic Carcinoma[J]. Journal of Capital Medical University, 2008, 29(1): 26-28.

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