首都医科大学学报 ›› 2010, Vol. 31 ›› Issue (1): 4-7.

• 奖项介绍 • 上一篇    下一篇

阻塞性睡眠呼吸暂停低通气综合征研究和诊治——2009年度国家科学技术进步二等奖

韩德民   

  1. 首都医科大学附属北京同仁医院,北京市耳鼻咽喉科研究所
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2010-02-21 发布日期:2010-02-21

The Second Grade National Prize for Science and Technology Progress——Studies on Diagnosis and Treatment for Obstructive Sleep Apnea and Hypopnea Syndrome

HAN De-min   

  1. Beijing Tongren Hospital, Capital Medical University; Beijing Institute of Otorhinolaryngology
  • Received:1900-01-01 Revised:1900-01-01 Online:2010-02-21 Published:2010-02-21

摘要:

该项目针对评估睡眠呼吸暂停低通气综合征(obstructive sleep apnea and hypopnea syndrome,OSAHS)不同个体的关键致病因素,重塑气道结构,提高手术疗效,避免合并症的技术难题,首次提出腭帆间隙的解剖概念;创建了解剖腭帆间隙、切除间隙内沉积脂肪、保留悬雍垂的一期腭咽成形术(uvulopalatopharyngoplasty,H-UPPP),提高了手术疗效,无1例严重合并症。建立选择手术适应证及综合治疗体系,选择手术适应证使显效率由53.3%提高到82.4%,实现围手术期无死亡。提出“结构功能症状”的创新学术理念,成功地将鼻内镜外科技术应用于OSAHS治疗。技术推广至全国17个省、自治区及直辖市,30个医疗机构,主持制订了我国专科领域第一个OSAHS诊疗指南。发表论文196篇(SCI 20篇)。授权专利7项。手术技术写入国家级教材并在国外专著中作独立章节介绍。该项目开发的新技术作为OSAHS安全有效的治疗方法,从源头上降低了心脑血管等多种严重危害人类健康常见多发病的发病率,明显提高了群体生活质量。

关键词: 睡眠呼吸暂停, 诊断, 治疗

Abstract:

This study was designed to improve diagnosis and the effectiveness of surgical treatment for obstructive sleep apnea and hypopnea syndrome. By establishing the concept of veli palatine, popularizing a revised uvulopalatopharyngoplasty(Han-UPPP), the surgical complications were reduced. Effectiveness of surgical treatment was improved from 53.3% to 82.4% by locating the obstructive sites in patients with sleep apnea and standardizing the indications of upper airway surgery. Death in perioperative period was diminished. The concept of "structure, function and symptom" was established. And endoscopic management of nasal obstruction was pushed to improve nasal breathing in patients with sleep apnea. The technologies were popularized in 17 provinces and over 30 hospitals in china. The guideline of diagnosis and treatment of sleep apnea in China was established. 196 related articles were published, including 20 in journals of scientific citation index. Seven patents were granted. The normalized techniques and basic studies about obstructive sleep apnea were enhanced, which resulted in the improvement of diagnosis and treatment level in China.

Key words: sleep apnea, diagnosis, treatment

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