首都医科大学学报 ›› 2010, Vol. 31 ›› Issue (1): 48-50.

• 眼科学基础及临床研究进展 • 上一篇    下一篇

白内障术前患者角膜内皮细胞减少原因的探讨

侯艳丽, 王艳玲   

  1. 首都医科大学附属北京友谊医院眼科
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2010-02-21 发布日期:2010-02-21
  • 通讯作者: 王艳玲

Factors Related to Decreased Corneal Endothelial Cell Density in Patients Prior to Cataract Surgery

HOU Yan-li, WANG Yan-ling   

  1. Department of Ophthalmology, Beijing Friendship Hospital, Capital Medical University
  • Received:1900-01-01 Revised:1900-01-01 Online:2010-02-21 Published:2010-02-21
  • Contact: WANG Yan-ling

摘要: 目的 探讨白内障手术前患者角膜内皮细胞减少的原因以及角膜内皮检查在白内障术前的重要性。方法 回顾首都医科大学附属北京友谊医院眼科白内障术前803例1 606眼角膜内皮细胞密度检查结果,其中男性336 例,女性467例,年龄29~95岁,平均年龄75岁。无内眼手术史,诊断标准:各个年龄段角膜内皮正常值(平均值-2×标准差)。结果 角膜内皮细胞减少82例(10.2%)112眼,角膜内皮减少原因为: 糖尿病(22.0%)、青光眼(7.3%)、异位性皮炎(2.4%)、虹膜劈裂(1.2%)、过熟期白内障(6.1%)、晶体半脱位(11.0%)和外伤(3.7%)。原因不明38例(46.3%)54眼。结论 约10%白内障患者术前角膜内皮细胞减少但普通眼科检查不能发现,为避免严重合并症产生,术前角膜内皮细胞的检查是必要的。

关键词: 白内障, 角膜内皮, 眼科检查

Abstract: Objective To explore the causes of decrease in corneal endothelial cells and the importance of examining the corneal endothelial cells in patients prior to cataract surgery. Methods The series comprised 336 male and 467 female patients. Their age ranged from 29 to 95 years, average 75 years. Decrease in corneal endothelial cell density was defined as reduction by twice the standard deviation from the known value for healthy persons in each age group. Results Eightytwo of the patients(10.2%) had decreased corneal endothelial cell density. The presumed underlying causes were diabetes mellitus(22.0%), glaucoma(7.3%), atopic dermatitis(2.4%) and others. No causes could be identified in 38 cases(46.3%). Conclusion Reduction in endothelial cells is present in about 10% of cases awaiting cataract surgery. We advocate evaluation of corneal endothelial cells as a routine procedure prior to intraocular surgery.

Key words: cataract, corneal endothelium, ophthalmologic examination

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