首都医科大学学报 ›› 2011, Vol. 32 ›› Issue (1): 46-49.

• 耳鼻咽喉头颈外科基础与临床研究 • 上一篇    下一篇

耳鸣治疗的影响因素分析

丁雷1,2,刘博1,2*,王嘉玺3,刘大新3   

  1. 1. 首都医科大学附属北京同仁医院耳鼻咽喉头颈外科; 2. 教育部耳鼻咽喉头颈外科重点实验室,北京市耳鼻咽喉科学研究所; 3. 北京中医药大学东方医院耳鼻喉科
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2011-02-21 发布日期:2011-02-21
  • 通讯作者: 刘博

Regression Analysis of the Effects of Tinnitus

DING Lei1,2, LIU Bo1,2*, WANG Jia-xi3, LIU Da-xin3   

  1. 1. Department of Otorhinolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University; 2. Key Laboratory of Otorhinolaryngology Head and Neck Surgery, Ministry of Education, Beijing Institute of Otorhinolaryngology; 3. Department of Otorhinolaryngology, Dongfang Hospital Affiliated to Beijing University of Chinese Medicine
  • Received:1900-01-01 Revised:1900-01-01 Online:2011-02-21 Published:2011-02-21
  • Contact: LIU Bo

摘要: 目的 通过电针刺激与口服药物进行耳鸣临床治疗的观察,评估对耳鸣患者采取干预措施的价值,并运用多元线性回归法分析治疗中的可能影响因素。
方法 将病程大于3个月的主观性耳鸣患者80例,根据就诊顺序分为针灸治疗组与药物治疗组(每组40例),针灸组采用听宫穴为主穴并通脉冲刺激,每次15 min,每日1次,20次为一疗程;口服组给予甲钴胺、银杏叶片连续20 d为一疗程。疗程结束后根据疗效评定标准评价疗效,分析影响耳鸣临床疗效的可能因素。
结果 ① 2组有效率分别为52.5%和37.5%,组间疗效差异无统计学意义(P=0.082);② 由回归方程可知:疗效与耳鸣持续时间呈负相关,具有统计学意义(P=0.000)。
结论 对耳鸣患者采取干预治疗措施是有意义的,治疗方案应遵循综合性、个体化,早期进行治疗者预后更为乐观。

关键词: 耳鸣, 治疗, 影响因素, 回归分析

Abstract: Objective To observe the clinical efficacy of electroacupuncture at acupoints in front of ears with drug treatment on tinnitus, to evaluate the interventions, and to analyze the possible factors influencing the treatment with the method of multivariate linear stepwise regression.
Methods Eighty cases with chronic subjective tinnitus in whom ringing in the ears was the first complaint and course of more than 3 months were enrolled in this study. The patients were randomly divided into acupuncture group and drug control group, 40 cases in each. In the acupuncture group the main points in front of ears were adopted and were treated through pulse stimulation, the needles were left for fifteen minutes each time, once a day and twenty times formed a course. The patients in the drug control group were given oral tablets, Ginkgo and Mecobalamin for 20 consecutive days. After the treatment, evaluation was made according to standards, and analyses were performed for factors that may affect efficacy of tinnitus.
Results Efficiency of the two groups were 52.5% and 37.5%, there was no significant difference(P=0.082). The effect Y had a negative correlation with the course X2.
Conclusion Intervention with both the acupuncture and drug treatments was effective for patients with tinnitus.

Key words: tinnitus, treatment, relevant factors, regression analysis

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