首都医科大学学报 ›› 2012, Vol. 33 ›› Issue (2): 280-283.doi: 10.3969/j.issn.1006-7795.2012.02.031

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肿瘤干细胞在子宫内膜癌的诊断与治疗中的研究进展

崔开宇, 孔宪超   

  1. 哈尔滨医科大学附属第二医院妇产科,哈尔滨 150081
  • 收稿日期:2011-08-29 修回日期:1900-01-01 出版日期:2012-04-21 发布日期:2012-04-21
  • 通讯作者: 孔宪超

Advances in studies on cancer stem cell in diagnosis and treatment of endometrial carcinoma

CUI Kai-yu, KONG Xian-chao   

  1. Department of Obstetrics and Gynecology, The 2nd Affiliated Hospital of Harbin Medical University Department of Obstetrics and Gynecology, Harbin 150081, China
  • Received:2011-08-29 Revised:1900-01-01 Online:2012-04-21 Published:2012-04-21

摘要: 肿瘤干细胞(cancer stem cell,CSC)由于其具有自我更新、高分化潜能、高致瘤性等特性,目前,在血液肿瘤、乳腺癌、脑肿瘤及前列腺癌等疾病的研究中取得了一定的进展。但是,各种CSC的鉴定与分离都还处在探索阶段。本文复习了子宫内膜癌、肿瘤干细胞及子宫内膜干细胞的概况,对肿瘤干细胞在子宫内膜癌的诊断与治疗方面的应用进展进行了综合阐述,并对其未来研究前景进行了讨论与展望。

关键词: 肿瘤干细胞, 子宫内膜癌, 诊断, 治疗

Abstract: With the characteristics of self-renewal, well-differentiated potency and oncogenicity, cancer stem cell(CSC) have drew the interests of researchers in the study of neoplastic hematologic disorder, breast cancer and prostatic carcinoma,and certain advances have occurred. However, the evaluation and isolation of CSC are still in the process of exploration. This article made a general review of endometrial carcinoma, CSC and endometrial stem cell. It gives a comprehensive description of the application CSC in diagnosis and treatment of endometrial carcinoma, and the future research prospect are discussed.

Key words: cancer stem cell, endometrial carcinoma, diagnosis

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