关键词: 黄体酮, 地屈孕酮, 妊娠

Abstract:

During human and mammalian pregnancy, endogenous progesterone is the dominant hormone since it is not only essential for conception and implantation, but also essential throughout pregnancy. Progesterone exerts its effects for prevention and treatment in human pregnancy by certain mechanisms. If one considers prevention or treatment with progestogens in human pregnancy, that all progestogens are progestogenic, if one considers the progestogens for prevention and therapeutic approaches, nowadays, only two progenstogens can be considered fully suitable for prevention and treatment in human pregnancy: progesterone and dydrogesterone. This review discusses the mechanism of progesterone and dydrogesterone in pregnancy and treatment in human.

Key words: progesterone, dydrogesteone, pregnancy