首都医科大学学报 ›› 2015, Vol. 36 ›› Issue (3): 465-468.doi: 10.3969/j.issn.1006-7795.2015.03.025

• 临床研究 • 上一篇    下一篇

早发型子痫前期期待治疗对围生儿结局影响因素分析

苗晓   

  1. 首都医科大学附属北京潞河医院产科, 北京 101149
  • 收稿日期:2015-01-23 出版日期:2015-06-21 发布日期:2015-06-15
  • 通讯作者: 苗晓 E-mail:jfff@sina.com

Expectant treatment of early onset preeclampsia influencing factors on perinatal outcome of children

Miao Xiao   

  1. Department of Obstetrics, Beijing Luhe Hospital, Capital Medical University, Beijing 101149, China
  • Received:2015-01-23 Online:2015-06-21 Published:2015-06-15

摘要:

目的 探讨早发型子痫前期期待治疗的适宜时间及终止妊娠时机.方法 回顾性分析自2012年4月至2014年4月在首都医科大学附属北京潞河医院治疗的65例早发型子痫前期患者的发病情况及妊娠结局,将65例患者根据发病孕周分为A、B两组.28~31+6周的38例为A组(58.5%,28/65),32~34周的27例为B组(41.5%,27/65).结果 A、B两组患者发病年龄、自觉症状、妊娠延长天数差异有统计学意义(P=0.000、P=0.028、P=0.000).A、B组并发HELLP(hemolysis,elevated liver enzymes,and low platelet syndrome, HELLP) 综合征及胎儿生长受限(fetal growth restriction,FGR) 的发生率差异有统计学意义(P=0.045、 P=0.000).A、B组分娩孕周、出生体质量差异有统计学意义(P=0.000,P=0.043).结论 早发型子痫前期围生儿结局与分娩孕周、出生体质量、孕妇发病的孕周密切相关,发病越早,病情越严重,围生儿合并症的发病率越高.尽早干预治疗,严密观察母婴安危,个性化的选择适宜的分娩孕周,可获得最佳的母婴结局.

关键词: 早发型子痫前期, 妊娠合并症, 围生儿结局, 期待治疗

Abstract:

Objective To study early-onset pre-eclampsia expectant management of appropriate timing and timing of pregnancy termination. Methods From April 2012 to April 2014 in our treatment of 65 patients with early-onset preeclampsia, according to gestational 28-31+6 weeks of onset for A group of 38 patients (58.5%,28/65), 32-34 weeks gestational age of onset Group B in 27 cases (41.5%,27/65) were conducted a retrospective analysis of the incidence and outcome of patients. Results The patient age, symptoms, average prolong pregnancy between A and B group have significant differences (P=0.000, P=0.028,P=0.000). HELLP Syndrome and FGR between A and B group has significant difference (P=0.045, P=0.000). The patient gestational age, birth weight of the two group have significant differences (P=0.000, P=0.043). Conclusion Early-onset preeclampsia and perinatal outcomes gestational weeks and birth weight, gestational age of onset for pregnant women is closely related to the disease earlier, more serious illness, higher perinatal morbidity. Treatment must intervene as soon as possible, and close observation of the mother and child safety, personalized selection of gestational weeks, to get the best maternal and neonatal outcomes.

Key words: early onset pre-eclampsia, pregnancy complications, perinatal outcome of children, expectant treatment

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