首都医科大学学报 ›› 2007, Vol. 28 ›› Issue (4): 513-515.

• 临床研究 • 上一篇    下一篇

成人创伤性脑损伤后早期应激性肝损害的临床分析

孟庆颖, 朱玉群   

  1. 首都医科大学附属北京天坛医院消化内科
  • 收稿日期:2006-07-17 修回日期:1900-01-01 出版日期:2007-08-24 发布日期:2007-08-24

Clinical Analysis of the Hepatic Stress Injury in Early Stage after Traumatic Brain Injury in Adults

Meng Qingying, Zhu Yuqun   

  1. Department of Gastroenterology, Beijing Tiantan Hospital, Capital Medical University
  • Received:2006-07-17 Revised:1900-01-01 Online:2007-08-24 Published:2007-08-24

摘要: 目的 探讨创伤性脑损伤后早期应激性肝损害(HSI)发病率、高危因素及预后。方法 回顾性分析329例创伤性脑损伤(TBI)患者的临床资料。结果 329例中发生早期HSI者49例,占创伤性脑损伤患者的14.9%。HSI的发生率和死亡率与颅脑损伤程度显著相关,与患者性别、年龄、损伤部位和损伤类型等方面无显著关系。结论 HSI可在创伤性脑损伤的早期发生,它的出现与损伤程度密切相关,临床预后不良,死亡率增加,应给予高度重视和积极干预。

关键词: 应激性肝损害, 创伤性脑损伤

Abstract: Objective To investigate the incidence,the risk factors and prognosis of the hepatic stress injury in early stage after traumatic brain injury in adults.Methods Total 329 cases with traumatic brain injury admitted and treated in our department from January 2005 to September 2005 were analyzed retrospectively.Results Forty-nine patients were diagnosed hepatic stress injury(14.9%).There is no difference in age,sex,injury type and site,between Group HSI and the control group.The degree of injury(GCS) in HSI is significantly more severe than the control(P<0.001).The mortality in HSI is increased(P<0.05).Conclusion HSI may appear in early stage after traumatic brain injury.There is close correlation between HSI and the degree of injury.The prognosis is not good,the total mortality is 30.6%.HSI needs more attention and active treatment.

Key words: hepatic stress injury(HSI), traumatic brain injury(TBI)

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