首都医科大学学报 ›› 2010, Vol. 31 ›› Issue (1): 11-17.

• 眼科学基础及临床研究进展 • 上一篇    下一篇

河北省永年县成年人主要致盲眼病现状调查:邯郸眼病研究进展报告

王宁利, 王凤华, 梁远波   

  1. 首都医科大学附属北京同仁医院, 北京同仁眼科中心, 北京市眼科学与视觉科学重点实验室
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2010-02-21 发布日期:2010-02-21
  • 通讯作者: 王宁利

The Handan Eye Study: A Review

WANG Ning-li, WANG Feng-hua, LIANG Yuan-bo   

  1. Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University; Beijing Ophthalmology and Visual Science Key Laboratory
  • Received:1900-01-01 Revised:1900-01-01 Online:2010-02-21 Published:2010-02-21
  • Contact: WANG Ning-li

摘要: 邯郸眼病研究是以人群为基础的横断面眼病流行病学研究,于2006至2007年经随机整群抽样在河北省邯郸市永年县13个村的30岁以上人群选取7 557人。所有入选人员进行既定的眼部和全身检查,以及进行标准问卷调查,主要内容包括自动验光、主观验光、自动血压计测量血压、身高、体质量、标准心电图、压平式眼压计测量眼压、裂隙灯检查、散瞳后眼底照相。并抽取空腹血样进行血糖、血脂、肾功能等生化检查。共完成6 830例受试者的检查,应答率为90.4%。本综述报告了邯郸眼病研究人群中盲、视力损害、屈光不正、糖尿病视网膜病变、视网膜前膜以及正常国人光学相干断层成像(optical coherence tomography,OCT)测量黄斑厚度值等的数据。邯郸眼病研究的数据将为我国北方农村地区人群的主要致盲性眼病的患病情况提供重要信息,从而为我国公共卫生领域防盲政策的制定等提供参考依据。

关键词: 邯郸眼病研究, 流行病学, 眼科学, 人群为基础的研究

Abstract: The Handan Eye Study is a population-based and epidemiological investigation of cross-sectional ophthalmopathy which included 6 830 Han people from 7 557 subjects at the age over 30 years in 13 villages of Yongnian County, Handan city, Hebei province in 2006-2007. The interviews covered demographic, behavioral, and ocular risk factors as well as healthrelated and vision-related quality of life. Ocular examination included measurement of visual acuity(VA), intraocular pressure, anterior and posterior segment examinations, visual field testing, fundus and optic disc photography. Physical examination included measurement of height and weight, blood pressure, electrocardiogram, fasting blood glucose, lipid levels, urea nitrogen and creatinine as well as tests of physical function including walking speed. Of the 7 557 individuals eligible for Handan Eye Study(HES), 6 830(90.4%) subjects participated the study. We present normative data for refractive error, frequency and causes of visual impairment and blindness, prevalence of epiretinal membranes, diabetic retinopathy and the normal OCT-measured macular thickness in healthy eyes of adult Chinese persons. These data from the HES will provide key information about the prevalence, risk factors, impact, and trends of ocular disease in rural regions of China and may be helpful for dealing with public health issues in China.

Key words: Handan eye study, epidemiology, ophthalmology, populationbased study

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