首都医科大学学报 ›› 1995, Vol. 16 ›› Issue (4): 293-295.

• 论著 • 上一篇    下一篇

华蟾素治疗慢性乙型肝炎33例临床观察

高庆林1, 李郁英1, 郭建强1, 李玉彬2   

  1. 1. 首都医学院;2. 海军总医院传染科
  • 收稿日期:1995-02-27 修回日期:1900-01-01 出版日期:1995-10-15 发布日期:1995-10-15

Clinical Observation of Therapeutic Effects on Hepatitis B Virus by Cinobufacini

Gao Qinglin1, Li Yuying1, Guo Jianqiang1, Li Yubin2   

  1. 1. Capital Institute of Medicine;2. Department of Infections Diseases, The General Naval Hospital
  • Received:1995-02-27 Revised:1900-01-01 Online:1995-10-15 Published:1995-10-15

摘要: 采用华蟾素治疗慢性乙型肝炎33例(对照组32例).治疗组除与对照组应用相同治疗外,加用华蟾素4mL肌注1次/d,45d为1疗程。1疗程结束后治疗组HBeAg和HBV-DNA阴转率分别为44.84%和34.61%,而对照组HBeAg和HBV-DNA阴转率分别为7.14%和0.提示华蟾素治疗慢性乙型肝炎近期疗效确切。

关键词: 乙型肝炎病毒, 乙型肝炎, 华蟾素, 阴转率

Abstract: 33 cases of chronic hepatitis B (32 cases for control) were treated by cinobufacini.The same management was used for both control and treating groups ,except an additional treatment by injecting 4 mL of cinobufacini per day intramuscularly,for the treating group.There were 45 days in one course of treatment.Afrer one course,the negative conversion rates of HBeAg and HBV-DNA in the treating group were 44.84% and 34.61% respectively, while in the control group they were only 7.14% and 0 respectively.This observation suggests that short-term effect of cinobufacini is rather satisfactory for treating the chronic hepatitis B.

Key words: hepatitis B virus, hepatitis B, cinobufacini, negative conversion rate

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