首都医科大学学报 ›› 2002, Vol. 23 ›› Issue (2): 156-158.

• 临床研究 • 上一篇    下一篇

静脉移植法建立犬动脉瘤模型

尹可, 丁艳玲, 吴中学, 杨新健   

  1. 北京神经外科研究所
  • 收稿日期:2001-01-10 修回日期:1900-01-01 出版日期:2002-04-15 发布日期:2002-04-15

Experience of Construction of Canine Aneurysnal Models with Fransplantation of Venous Pouches

Yi Ke, Ding Yanling, Wu Zhongxue, Yang Xinjian   

  1. Beijing Neurosurgical Institute
  • Received:2001-01-10 Revised:1900-01-01 Online:2002-04-15 Published:2002-04-15

摘要: 为探讨建立犬的侧方、分叉部和顶端动脉瘤模型的方法,在全麻下将静脉袋吻合于重建的颈总动脉,建立动脉瘤模型。术后1~3周动物行数字减影造影(DSA)评估动脉瘤模型。共成功建立分叉部动脉瘤9个,顶端动脉瘤8个,侧方动脉瘤15个。有1只动物因为麻醉过量而死亡,1只动物因顶端动脉瘤破裂死亡;1只犬的分叉部动脉瘤和侧方动脉瘤连同载瘤动脉完全闭塞,3个侧方动脉瘤自发闭塞,1个顶端动脉瘤术后3周自发破裂并形成假性动脉瘤。研究表明,用静脉袋移植法建立动脉瘤模型的方法手术成功率高,并发症少,是一种较理想的方法。

关键词: 动脉瘤, 模型, 静脉袋

Abstract: The research explored the methods of production of canine models of lateral, bifurcation and terminal arterial aneurysms. Aneurysmal models were constructed by anastomosing venous pouches onto the rebuilt common carotid arteries under general anesthesia. The experimental aneurysms were evaluated by digital subtraction angiography(DSA)after 1 to 3 weeks. Fifteen lateral aneurysms, 9 bifurcation aneurysms and 8 terminal aneurysms were obtained Successfully. One animal died of over-dosed anesthesia. Another died from rupture of a terminal aneurysm. One dog had its bifurcation aneurysm, lateral aneurysm and parent arteries completely thrombosed, 3 had their lateral aneurysms occluded spontaneously, and one had its terminal aneurysm ruptured to form pseudoaneurysm 3 weeks after operation. The results demonstrate that construction of aneurysmal models by anastomosing the venous porches is a ideal method with a highly successful rate of surgery and fewer complications.

Key words: aneurysms|models|venous pouch

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