首都医科大学学报 ›› 2004, Vol. 25 ›› Issue (3): 298-301.

• 论著·基础研究 • 上一篇    下一篇

移动电话微波辐射对小鼠机体影响的形态学观察

刘瑜1, 刘国贞1, 董小黎1, 宋爱利1, 陈安宇2   

  1. 1. 首都医科大学基础医学院病理学教研室;2. 首都医科大学生物医学工程学院
  • 收稿日期:2003-11-20 修回日期:1900-01-01 出版日期:2004-07-15 发布日期:2004-07-15

Morphologic Observation of Effect of Mobile Telephone Microwave Radiation on Mouse

Liu Yu1, Liu Guozhen1, Dong Xiaoli1, Song Aili1, Chen Anyu2   

  1. 1. Department of Pathology, Capital University of Medical Sciences;2. Biomedical Engineering College, Capital University of Medical Sciences
  • Received:2003-11-20 Revised:1900-01-01 Online:2004-07-15 Published:2004-07-15

摘要: 为探讨移动电话微波辐射对机体的影响,采用SP免疫组织化学染色法,观察小鼠海马、小脑中神经元型一氧化氮合酶(nNOS)的变化;常规HE染色观察微波辐射后小鼠主要脏器改变.结果:与正常对照组相比,各微波照射组海马处NOS染色无明显变化,小脑处NOS染色除45MHz组无明显变化外,其余3组均表现为NOS染色加深.各微波照射组心、肝、脾、肺、肾及大脑未见明显病理改变.提示:移动电话对小鼠主要脏器及海马可能不会产生明显损害,而对小脑神经细胞可能存在一定损伤作用,有可能影响小脑的正常功能.

关键词: 移动电话, 微波辐射, 一氧化氮, 海马, 小脑

Abstract: In order to explore the effect of mobile telephone microwave radiation on mouse, the expression of synthase(NOS) in hippocampus and cerebellum and the changes of primary organs of mouse was studied following exposure to the mobile telephone microwave radiation.SP immunohistochemical staining was employed to detect the expression of NOS; HE staining was used to observe histopathological changes.Compared with normal control group,the intensity of positive staining in cerebellum was increased after exposure to microwave radiation(450, 870, 2 450 MHz).The expression of NOS in hippocampus and the primary organs of mouse had no obvious change.The results indicate the increase of NOS expression in cerebellum possibly has effect on the function of cerebellum of mouse after exposure to microwave radiation, but further discussion and investigation is necessary.

Key words: mobile telephone, microwave radiation, nitric oxide, hippocampus, cerebellum

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