首都医科大学学报 ›› 2004, Vol. 25 ›› Issue (3): 341-344.

• 论著·临床研究 • 上一篇    下一篇

肝病患者革兰阴性细菌感染的临床分析

张文中, 郭秋艳, 刘海霞   

  1. 首都医科大学附属北京佑安医院感染科
  • 收稿日期:2004-05-20 修回日期:1900-01-01 出版日期:2004-07-15 发布日期:2004-07-15

G- Bacteria Infection in Patients with Hepatic Disease

Zhang Wenzhong, Guo Qiuyan, Liu Haixia   

  1. Department of Infections Diseases, Beijing Youan Hospital, Affiliate of Capital University of Medical Sciences
  • Received:2004-05-20 Revised:1900-01-01 Online:2004-07-15 Published:2004-07-15

摘要: 从肝病患者的体液及血液中分离、鉴定革兰阴性细菌菌株,同时测定革兰阴性细菌产超广谱β-内酰胺酶率及对抗生素的耐药情况,以了解细菌感染的分布,为临床合理用药提供依据.结果:肝病患者革兰阴性病原菌以大肠杆菌、肺炎克雷伯菌和气单胞菌属占多数.产酶株主要分布在肺炎克雷伯菌和大肠杆菌,其敏感性低于非产酶株.提示:临床上应根据药敏结果合理选用抗生素.

关键词: 肝病, 革兰阴性菌, 超广谱β-内酰胺酶类, 耐药性

Abstract: To investigate the spectrum of bacteria isolated from hepatitis and characteristics of drug resistance and to evaluate the clinical preventive and therapeutic measures, the bacterial spectrum separated from blood/body fluids of patient with hepatitis were examined to estimate the ability of producing enzyme.And their drug resistance and clinical characteristics were analysed.Result of the G- bacteria, Escherichia coli, Klebsiella pneumoniae and aeromonas strains were the major ones.The bacteria producing beta-lactamase were mainly from Escherichia coli and Klebsiella pneumoniae and their susceptibilities to antibiotic were lower than those of no enzyme product bacteria.The result indicates that antibiotics should be selected based on susceptibility.

Key words: hepatitis, G- bacteria, beta-lactamase, bacterial resistance

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