首都医科大学学报 ›› 2003, Vol. 24 ›› Issue (4): 457-459.

• 论著·临床研究 • 上一篇    下一篇

重症SARS的缺氧性脑损害与氧治疗

宿英英, 楚长彪   

  1. 首都医科大学宣武医院神经内科
  • 收稿日期:2003-07-23 修回日期:1900-01-01 出版日期:2003-10-15 发布日期:2003-10-15

Anoxic Brain Damage and Oxygen Therapy of Severe SARS

Su Yingying, Chu Changbiao   

  1. Neurological Department of Xuanwu Hospital, Affiliate of Capital University of Medical Sciences
  • Received:2003-07-23 Revised:1900-01-01 Online:2003-10-15 Published:2003-10-15

摘要: 为探讨重症SARS患者的缺氧性脑损害及氧治疗的效果,用回顾性研究的方法对2003年5月至6月,我院收治的伴有严重低氧血症的84例重症SARS患者进行缺氧性脑功能损害的调查。结果54例(64.3%)患者出现缺氧性脑损害表现,其中运动迟缓和懒言少语最为突出(92.6%),其次是情绪改变(46.3%),精神抑郁或焦虑(40.7%)、意识障碍(22.2%)、认知功能障碍(9.3%)和惊厥(1.9%)。通过调整最佳供氧方式,提高氧流量,减少氧耗等氧治疗,使缺氧表现在短时间(平均5d)内得到改善,呼吸减慢、心率下降、脉搏血氧饱和度(SpO2)增高和缺氧性脑损害症状消失。提示SARS患者的缺氧性脑损害不容忽视,正确的氧治疗可提高治愈率,降低病死率。

关键词: SARS, 缺氧性脑损害, 氧治疗, 预后

Abstract: The objective was to study anoxic brain damage of severe SARS and to investigate the effect of the oxygen therapy.All the 149 patients suffered from severe SARS were treated in Xuanwu Hospital from May 2003 to June 2003.The degree of Anoxic brain damage of84cases with severe hypoxemia were evaluated retrospectively.Result:54cases(64.3%)presented the manifestation of Anoxic brain damage.Among them bradypraxia and less verbal communication were the most common syndrome(92.6%),others included emotional disorder(46.3%),depression or anxiety(40.7%),conscious disturbance(22.2%),cognitive dysfunction(9.3%)and convulsion(1.9%).Through adjusting the model of oxygen supply,the Anoxic syndrome could be improved in a relatively short period(average5d).The patients'breath rate and heart rate decreased,SpO2 increased and the Anoxic syndrome disappeared.Anoxic brain damage is a significant syndrome and should not be neglected,furthermore correct and reasonable oxygen therapy can increase the curability and decrease the mortality rate of SASR patient.

Key words: SARS, anoxic brain damage, oxygen therapy, prognosis

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