首都医科大学学报 ›› 2004, Vol. 25 ›› Issue (4): 516-518.

• 论著·临床研究 • 上一篇    下一篇

1670例慢性浅表性胃炎感染幽门螺杆菌情况分析

王岸柳, 李洪利, 赵同建   

  1. 首都医科大学附属北京天坛医院病理科
  • 收稿日期:2003-09-26 修回日期:1900-01-01 出版日期:2004-10-15 发布日期:2004-10-15

Helicobacter Pylori Infection in 1 670 Patients with Chronic Superficial Gastritis

Wang Anliu, Li Hongli, Zhao Tongjian   

  1. Department of Pathology, Beijiing Tiantan Hospital, Affiliate of Capital University of Medical Sciences
  • Received:2003-09-26 Revised:1900-01-01 Online:2004-10-15 Published:2004-10-15

摘要: 为进一步阐明慢性浅表性胃炎(CSG)与幽门螺杆菌(HP)感染的关系及CSG患者HP感染与年龄和性别的关系,对1 670例经临床、胃镜及病理均诊断为CSG的活检标本的HE及Giemsa染色切片进行回顾性观察,观察HE染色切片确定CSG的程度及是否伴有活动性炎症,观察Giemsa染色切片确定有无HP感染.结果:非活动性轻、中、重度CSG的HP检出率分别为7.35%、31.02%和52.03%,两两比较统计学上有显著性差异(P<0.01).活动性轻、中、重度CSG的HP检出率分别为66.67%,71.81%和89.43%,与相对应的非活动性轻、中、重度CSG的HP检出率相比差异非常显著(P<0.01).HP检出率男性为36.92%,女性为33.01%,两者比较无显著性差异(P>0.05).30岁以下组、31~60岁组、61岁以上组HP检出率分别为33.92%、37.90%和28.74%,经检验31~60岁组与61岁以上组差异非常显著(P<0.01).结果提示:HP是使CSG产生活动性并且使CSG程度加重的重要原因,但不是唯一因素.CSG病人HP感染率无性别差异,感染多发生在31~60岁人群.

关键词: 慢性浅表性胃炎, 幽门螺旋杆菌

Abstract: The aim was to illustrate the relationship between HP infection and CSG and the relationship between HP infection in CSG patients and age and gender. Retrospectively and histologically the biopsy specimens were doserved in 1 670 patients who were diagnosed as CSG clinically, endoscopically and histologically by HE staining and Giemsa staining to determine the severity and activity of CSG. The biopsy specimens were observed by Giemsa staining to determine HP infection. The incidences of HP in non-active mild, moderate and severe CSG patients were 7.35%, 31.02%, 52.03% respectively, the difference between any two incidences of the three was of statistical significance(P< 0.01), the incidences of HP in active mild,moderate and severe CSG patients were 66.67%, 71.81%, 89.43% respectively, and the difference between the incidences of HP in active mild, moderate and severe CSG patients and the correspondents in non-active CSG patients were of statistical significance(P<0.01). The incidence of HP in male patients was 36.92%, and in female patients was 33.01%. No statistical difference existed between two groups(P>0.05). the incidences of HP in age-group ≤30 years, 31~60 years and ≥61years were 33.92%, 37.90%, 28.74% respectively, with statistical difference only between age-group 31~60 years and ≥61 years(P<0.01). HP infection is a important factor that makes non-active CSG turn into active CSG; HP infection induces increase in the severity of CSG; there is no difference in the incidence of HP between male and female CSG patients; In CSG patients,HP infection is found most commonly in age-group 31~60 years.

Key words: chronic superficial gastritis, helicobacter pylori

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