槲芪散联合经动脉化疗栓塞术治疗原发性肝癌65例临床观察

首都医科大学学报 ›› 2009, Vol. 30 ›› Issue (1): 37-40.

槲芪散联合经动脉化疗栓塞术治疗原发性肝癌65例临床观察

杨薇¹, 杨华升¹, 何秀娟², 李秀惠¹, 钱英¹

1. 首都医科大学附属北京佑安医院中西医结合科;2. 首都医科大学基础医学院免疫学系

收稿日期:2008-11-18 修回日期:1900-01-01 出版日期:2009-02-21 发布日期:2009-02-21
通讯作者: 杨华升

Clinical Observation of 65 Cases with Hepatocellular Carcinoma Treated by Huqisan and Transeatheter Arterial Chemoembolization

Yang Wei¹, Yang Huasheng¹, He Xiujuan², Li Xiuhui¹, Qian Ying¹

1. Department of Integrated Traditional Chinese and Western Medicine, Beijing Youan Hospital, Capital Medical University;2. Department of Immunology,School of Basic Medical Science, Capital Medical University

Received:2008-11-18 Revised:1900-01-01 Online:2009-02-21 Published:2009-02-21

摘要/Abstract

摘要： 目的观察中药复方槲芪散联合经动脉化疗栓塞术治疗原发性肝癌对患者生存时间、生活质量及免疫功能的影响。方法 65例原发性肝癌患者用数字表法随机分为槲芪散治疗组和对照组,对照组给予槐耳颗粒,均治疗24周。比较2组患者外周血T淋巴细胞亚群和生活质量(KPS评分)变化、生存时间及临床总证候疗效。结果槲芪散治疗组在外周血T淋巴细胞亚群和生活质量(KPS评分)变化、生存时间及临床总证候疗效方面均优于对照组。结论槲芪散联合动脉化疗栓塞治疗原发性肝癌可明显提高总有效率,改善患者生活质量,延长生存期,提高患者细胞免疫功能,对肝癌的介入治疗可发挥增效减毒的作用。

关键词: 原发性肝癌, 槲芪散, 经动脉化疗栓塞, 免疫功能, 槐耳颗粒

Abstract: Objective To observe the joint effects of Chinese medicine Huqisan(HQS) and transcatheter arterial chemoembolization(TACE) in patients with hepatocellular carcinoma(HCC) on survival time, quality of life and immune function. Methods Sixty-five patients with HCC were randomly divided into two groups: the treatment group with HQS and TACE, and the control group with Huaier Keli. After the treatment for 24 weeks, the differences in peripheral T-lymphocyte subsets, quality of life(KPS), survival time and clinical efficacy of the overall syndrome were analyzed. Results The treatment group was better than the control group in terms of peripheral blood T-lymphocyte subsets, the quality of life(KPS), survival time and clinical efficacy of the overall syndrome. Conclusion The treatment of HQS and TACE for HCC may improve the overall efficacy and the quality of life, survival time and cell immune function of patients.

Key words: hepatocellular carcinoma, Huqisan, transeatheter arterial chemoembolization, immune function, Huaierkeli

中图分类号:

R 4/78

杨薇;杨华升;何秀娟;李秀惠;钱英. 槲芪散联合经动脉化疗栓塞术治疗原发性肝癌65例临床观察[J]. 首都医科大学学报, 2009, 30(1): 37-40.

Yang Wei;Yang Huasheng;He Xiujuan;Li Xiuhui;Qian Ying. Clinical Observation of 65 Cases with Hepatocellular Carcinoma Treated by Huqisan and Transeatheter Arterial Chemoembolization[J]. Journal of Capital Medical University, 2009, 30(1): 37-40.

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