首都医科大学学报 ›› 2014, Vol. 35 ›› Issue (2): 210-213.doi: 10.3969/j.issn.1006-7795.2014.02.014

• 精神科基础和临床 • 上一篇    下一篇

具有神经保护作用的中药有效成分研究进展

庄红艳1, 毕葳2, 贾竑晓3,4   

  1. 1. 首都医科大学附属北京安定医院药剂科, 北京 100088;
    2. 中医科学院中药研究所中药室, 北京 100700;
    3. 北京市中西医结合精神卫生研究所, 北京 100088;
    4. 北京脑重大疾病研究院精神分裂症研究所, 北京 100088
  • 收稿日期:2014-02-18 出版日期:2014-04-21 发布日期:2014-04-16
  • 基金资助:

    北京市中医药科技发展基金资助项目(JJ2009-19)。

Research progress in studies on the active ingredients of the traditional Chinese medicine with the neuroprotective effects

Zhuang Hongyan1, Bi Wei2, Jia Hongxiao3,4   

  1. 1. Department of Pharmacy, Beijing Anding Hospital, Capital Medical University, Beijing 100088, China;
    2. Institute of Chinese Materia Medica, Chinese Academy of Chinese Medical Science, Beijing 100700, China;
    3. Institute of Mental Health of Combined Traditional Chinese and Western Medicine of Beijing, Beijing 100088, China;
    4. Center of Schizophrenia, Beijing Institute for Brain Disorders, Beijing 100088, China
  • Received:2014-02-18 Online:2014-04-21 Published:2014-04-16
  • Contact: 贾竑晓 E-mail:jhxlj@ccmu.edu.cn
  • Supported by:

    This study was supported by Beijing Technology Development Grant of Traditional Chinese Medicine(JJ2009-19).

摘要:

通过查阅国内外相关文献,对中药中皂苷类、黄酮类、生物碱类、酚酸类等具有神经保护作用的有效成(组)分进行了概述整理。中药有效成(组)分在神经保护机制上具有多靶点、多途径的优势,在神经损伤性疾病的预防和治疗方面有巨大的潜力。

关键词: 中药, 神经保护, 有效成分, 研究进展

Abstract:

An online search of Medline was undertaken to identify articles on studies on active ingredients of the traditional Chinese medicine(TCM) with neuroprotective effects.We summarized the activity and the mechanism of the ingredients in TCM, such as saponine, flavonoid, alkaloid and phenolic acid. TCM have advantage in the neuroprotective mechanism with multi-target and multi-channel, and there is a huge potential in the prevention and treatment of diseases of the nerve injury.

Key words: traditional Chinese medicine, neuroprotective effect, active ingredients, research progress

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