住院老年病人营养状况与衰弱相关性研究

doi:10.3969/j.issn.1006-7795.2017.03.010

首都医科大学学报 ›› 2017, Vol. 38 ›› Issue (3): 377-380.doi: 10.3969/j.issn.1006-7795.2017.03.010

• 心血管疾病的诊断与治疗 • 上一篇下一篇

住院老年病人营养状况与衰弱相关性研究

吕卫华, 王青, 赵清华, 吴薇, 翟雪靓, 张少景, 符琳琳

首都医科大学附属复兴医院干保科, 北京 100038

收稿日期:2017-01-14 出版日期:2017-05-21 发布日期:2017-06-14
通讯作者: 王青 E-mail:huaqi5371@medmail.com.cn
基金资助:
北京市保健科研课题项目（2015-15）。

Correlation between nutritional status and frailty in hospitalized elderly patients

Lyu Weihua, Wang Qing, Zhao Qinghua, Wu Wei, Zhai Xueliang, Zhang Shaojing, Fu Linlin

Department of Geriatrics, Fuxing Hospital, Capital Medical University, Beijing 100038, China

Received:2017-01-14 Online:2017-05-21 Published:2017-06-14
Supported by:
This study was supported by Health Care Scientific Research Project in Beijing (2015-15).

摘要/Abstract

摘要： 目的探讨老年住院病人营养状况与衰弱之间的关系，为营养干预改善老年衰弱状况提供依据。方法选取年龄≥ 65岁的老年住院病人371例，根据Fried衰弱表型评估（Fried's Cardiovascular Health Study index，CHS index）得分将病人分为无衰弱组、衰弱前期组及衰弱组，采用营养风险筛查（Mini Nutritional Assessment-Short Form，MNA-SF）及生物化学测定方法评估病人营养状态，分析营养状况对衰弱的影响。结果从无衰弱组到衰弱组MNA-SF分值、血红蛋白、白蛋白浓度逐渐降低，差异有统计学意义（P<0.01），营养不良和营养不良风险的发生率逐渐升高，分别为12.4%、38.3%、58.0%，差异有统计学意义（P<0.01）；Spearman相关分析显示，MNA-SF评分与衰弱呈负相关（r=-0.388，P<0.01），营养不良和营养不良风险与衰弱呈正相关（r=0.334，P<0.01）；Logistic回归分析显示，校正年龄、性别、血红蛋白、白蛋白、共病、多重用药等因素后，营养不良增加衰弱的发生风险（OR=7.650，95%CI：3.58~16.3，P<0.01）。结论老年住院病人衰弱状态与营养状况相关，营养不良可能是衰弱的重要危险因素。

关键词: 老年, 衰弱, 营养不良, 营养状况, 衰弱表型评估

Abstract: Objective To explore the relationship between the nutritional status and frailty in hospitalized elderly patients and provide evidence for the nutritional intervention to improve the elderly frailty status. Methods A total of 371 elderly hospitalized patients aged 65 and over were selected and divided into non-frail, pre-frail and frail groups according to the Fried's Cardiovascular Health Study index (CHS index). Mini Nutritional Assessment-Short Form (MNA-SF)and biochemical methods were used to assess the nutritional status of patients, and to analyze the effect of nutritional status on frailty. Results From non-frail group to frail group, the MNA-SF score, hemoglobin, albumin levels decreased gradually and the difference was statistically significant (P<0.01). The malnutrition and risk of malnutrition incidence increased gradually, which were 12.4%, 38.3% and 58.0%, respectively. The difference was statistically significant (P<0.01). Spearman correlation analysis showed that MNA-SF score was negatively correlated with frailty (r=-0.426, P<0.01) and the malnutrition and risk malnutrition were positively correlated with frailty (r=0.405, P<0.01). Logistic regression analysis showed that the malnutrition increased the risk of frailty after adjusting for age, sex, hemoglobin, albumin, comorbidity, multiple drug use and other factors(OR=7.650, 95%CI:3.58=16.3, P<0.01). Conclusion There was a correlation between frail state and nutritional status in hospitalized elderly patients. The malnutrition is the important risk factor of the frail state.

Key words: elderly, frail, malnutrition, nutritional status, Fried's Cardiovascular Health Study index(CHS index)

中图分类号:

R153.3

吕卫华, 王青, 赵清华, 吴薇, 翟雪靓, 张少景, 符琳琳. 住院老年病人营养状况与衰弱相关性研究[J]. 首都医科大学学报, 2017, 38(3): 377-380.

Lyu Weihua, Wang Qing, Zhao Qinghua, Wu Wei, Zhai Xueliang, Zhang Shaojing, Fu Linlin. Correlation between nutritional status and frailty in hospitalized elderly patients[J]. Journal of Capital Medical University, 2017, 38(3): 377-380.

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住院老年病人营养状况与衰弱相关性研究

Correlation between nutritional status and frailty in hospitalized elderly patients

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