关键词: 支撑喉镜术, 七氟烷, 丙泊酚, 瑞芬太尼, 静脉靶控输注系统

Abstract: Objective To compare propofol with sevoflurane with remifentanil target-controlled infusion(TCI) respectively during operation of suspension laryngoscopy. Methods Forty ASA Ⅰ-Ⅱ patients scheduled for the vocal cord surgery through suspension laryngoscopy were randomly divided into two groups: Propofol group(P group) and Sevoflurane group (S group), 20 cases in each. Both groups were induced with intravenous midazolam 1.0~1.5 mg, succinylcholine 1.5~2.0 mg/kg and remifentanil 4 μg/L in TCI. P group was induced with Propofol 3 μg/ml in TCI and S group with intravenous propofol 1.5~2.0 mg/kg. After intubation, patients in S group inhaled 2%~4% sevoflurane to get sevoflurane concentration to 1 MAC, and combined with remifentanil in TCI. Patients in P group were maintained with remifentanil and propofol in TCI. HR and MAP at different time point, waking time, extubation time and side effects were recorded and compared. Results In both groups after induction, the HR at T₁(1 min after induction) declined as compared with T₀(before operation)(P<0.05), and MAP at T₁ and T₂(1 min after intubation) declined as compared with T₀(P<0.05). But HR in P group at T₁, T₂ and T₇(operation finished) declined more significantly than that in S group(P<0.05). While waking time and extubation time in S group were shorter than in P group(P<0.05). Conclusion Both methods of anaethesia can achieve good effect in the suspension laryngoscopy, but the patients maintained with sevoflurane had more stable hemodynamics and recovered sooner.

Key words: suspension laryngoscopy, sevoflurane, propofol, remifentanil, target-controlled infusion