首都医科大学学报 ›› 2020, Vol. 41 ›› Issue (3): 433-438.doi: 10.3969/j.issn.1006-7795.2020.03.020

• 临床研究 • 上一篇    下一篇

肾移植病史心房颤动患者导管消融的安全性及有效性分析

喻荣辉1, 汤日波1, 吴嘉慧1, 闻松男1, 林晖2   

  1. 1. 首都医科大学附属北京安贞医院心脏内科中心, 北京 100029;
    2. 北京大学首钢医院心血管内科, 北京 100144
  • 收稿日期:2019-07-17 出版日期:2020-06-21 发布日期:2020-06-17
  • 通讯作者: 林晖 E-mail:cardiologylh@163.com
  • 基金资助:
    国家自然科学基金(81770322),北京市科技计划(Z181100001718174)。

Safety and efficacy of catheter ablation for atrial fibrillation patients with history of renal transplantation

Yu Ronghui1, Tang Ribo1, Wu Jiahui1, Wen Songnan1, Lin Hui2   

  1. 1. Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, China;
    2. Department of Cardiovascular, Beijing University Shougang Hospital, Beijing 100144, China
  • Received:2019-07-17 Online:2020-06-21 Published:2020-06-17
  • Supported by:
    This study was supported by National Natural Science Foundation of China (81770322), Beijing Municipal Science and Technology Project (Z181100001718174).

摘要: 目的 本研究讨论有肾移植病史的心房颤动(以下简称房颤)患者行导管消融的安全性及有效性。方法 以7例因抗心律失常药物治疗效果不佳而进行射频消融的有肾移植病史的房颤患者为病例组,按照1:6配对原则(年龄、性别和房颤类型)选择对照42例。对比分析复发率、围术期合并症和造影剂肾病发生率。结果 两组患者中均无围术期合并症和造影剂肾病的发生。在随访12个月时,有肾移植病史的房颤患者复发率更高(时序检验,P=0.027)。结论 有肾移植病史的房颤患者可以安全地施行射频消融术,但这类患者进行消融术后更容易复发。

关键词: 心房颤动, 肾移植, 估测的肾小球滤过率, 导管消融

Abstract: Objective To study the prognosis of catheter ablation in atrial fibrillation (AF) patients with history of renal transplantation. Methods Seven AF patients with renal transplantation history who had received radiofrequency ablation due to the poor effect of antiarrhythmic drugs were selected as the case group, and 42 controls were selected according to the 1:6 matching principle (age, gender and type of atrial fibrillation). The recurrence rate, perioperative complications and the incidence of contrast nephropathy were compared and analyzed. Results No periprocedural complications and contrast nephropathy were observed in either group. During a follow-up period of 12 months, the ATa recurrent rate was higher in AF patients with renal transplantation history (Log rank test, P=0.027). Conclusion Catheter ablation for AF can be safely performed in patients with history of renal transplantation. AF patients with renal transplantation history tend to have higher ATa recurrence after the catheter ablation.

Key words: atrial fibrillation, renal transplantation, estimated glomerular filtration rate, catheter ablation

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